type: position_score table: filename: ENCFF322WKG.tabix.bed.gz header_mode: none zero_based: true format: tabix chrom: column_index: 0 pos_begin: column_index: 1 pos_end: column_index: 2 scores: - id: TF_ChIP-seq_ENCSR932ZMX column_index: 3 type: float desc: signal histogram: type: number number_of_bins: 100 meta: summary: 'ChIP-seq ENCSR932ZMX [TISSUE: Homo sapiens GM23338 originated from GM23248, TARGET: CTCF]' description: "**status**: released\n\n**biological\\_replicates**: Rep 1, Rep 2\n\ \n**summary**: \n\n**output\\_type**: optimal IDR thresholded peaks\n\n**audit\\\ _internal\\_action**: File {ENCFF322WKG|/files/ENCFF322WKG/} with status 'released'\ \ is derived from file {ENCFF419RSJ|/files/ENCFF419RSJ/} with status 'archived'.\n\ \n**audit\\_internal\\_action**: Archived analysis {ENCAN757WCV|/analyses/ENCAN757WCV/}\ \ has in progress subobject quality standard {encode3-tf-chip|/quality-standards/encode3-tf-chip/}\n\ \n**audit\\_warning**: Processed alignments file {ENCFF102OPY|/files/ENCFF102OPY/}\ \ processed by ChIP-seq ENCODE3 GRCh38 pipeline has 16630680 usable fragments.\ \ The minimum ENCODE standard for each replicate in a ChIP-seq experiment targeting\ \ CTCF-human and investigated as a transcription factor is 10 million usable fragments.\ \ The recommended value is > 20 million, but > 10 million is acceptable. (See\ \ {ENCODE ChIP-seq data standards|/data-standards/chip-seq/} )\n\n**audit\\_warning**:\ \ Processed alignments file {ENCFF703HZB|/files/ENCFF703HZB/} processed by ChIP-seq\ \ ENCODE3 GRCh38 pipeline has 18576307 usable fragments. The minimum ENCODE standard\ \ for each replicate in a ChIP-seq experiment targeting CTCF-human and investigated\ \ as a transcription factor is 10 million usable fragments. The recommended value\ \ is > 20 million, but > 10 million is acceptable. (See {ENCODE ChIP-seq data\ \ standards|/data-standards/chip-seq/} )\n\n**audit\\_warning**: PBC1 (PCR Bottlenecking\ \ Coefficient 1, M1/M\\_distinct) is the ratio of the number of genomic locations\ \ where exactly one read maps uniquely (M1) to the number of genomic locations\ \ where some reads map (M\\_distinct). A PBC1 value in the range 0 - 0.5 is severe\ \ bottlenecking, 0.5 - 0.8 is moderate bottlenecking, 0.8 - 0.9 is mild bottlenecking,\ \ and > 0.9 is no bottlenecking. PBC1 value > 0.9 is recommended, but > 0.8 is\ \ acceptable. ENCODE processed alignments file {ENCFF102OPY|/files/ENCFF102OPY/}\ \ processed by ChIP-seq ENCODE3 GRCh38 pipeline was generated from a library with\ \ PBC1 value of 0.86.\n\n**audit\\_warning**: PBC1 (PCR Bottlenecking Coefficient\ \ 1, M1/M\\_distinct) is the ratio of the number of genomic locations where exactly\ \ one read maps uniquely (M1) to the number of genomic locations where some reads\ \ map (M\\_distinct). A PBC1 value in the range 0 - 0.5 is severe bottlenecking,\ \ 0.5 - 0.8 is moderate bottlenecking, 0.8 - 0.9 is mild bottlenecking, and >\ \ 0.9 is no bottlenecking. PBC1 value > 0.9 is recommended, but > 0.8 is acceptable.\ \ ENCODE processed alignments file {ENCFF703HZB|/files/ENCFF703HZB/} processed\ \ by ChIP-seq ENCODE3 GRCh38 pipeline was generated from a library with PBC1 value\ \ of 0.90." labels: reference_genome: hg38/genomes/GRCh38-hg38 accession: ENCSR932ZMX status: released assay_term_name: ChIP-seq simple_biosample_summary: '' biosample_summary: Homo sapiens GM23338 originated from GM23248 replication_type: isogenic biosample_ontology: /biosample-types/cell_line_EFO_0007950/ perturbed: false doi: 10.17989/ENCSR932ZMX date_created: '2015-12-16T21:50:51.860608+00:00' date_released: '2016-06-30' submitter_comment: 'This experiment is being used in the ENCODE-DREAM Transcription Factor Binding Site Prediction Challenge (https://www.synapse.org/#!Synapse:syn6131484/wiki/400026). The files will be unavailable until after the challenge completes on 09-30-16. UPDATE: There will be a second round to the challenge that is expected to end on 01-11-2017' target: CTCF