type: position_score table: filename: ENCFF932EVL.tabix.bed.gz header_mode: none zero_based: true format: tabix chrom: column_index: 0 pos_begin: column_index: 1 pos_end: column_index: 2 scores: - id: TF_ChIP-seq_ENCSR831EIW column_index: 3 type: float desc: signal histogram: type: number number_of_bins: 100 meta: summary: 'ChIP-seq ENCSR831EIW [TISSUE: Homo sapiens HEK293T, TARGET: FOXM1]' description: "**status**: released\n\n**biological\\_replicates**: Rep 1, Rep 2\n\ \n**summary**: \n\n**output\\_type**: optimal IDR thresholded peaks\n\n**audit\\\ _internal\\_action**: Archived analysis {ENCAN814AWP|/analyses/ENCAN814AWP/} has\ \ in progress subobject quality standard {encode3-tf-chip|/quality-standards/encode3-tf-chip/}\n\ \n**audit\\_warning**: PBC1 (PCR Bottlenecking Coefficient 1, M1/M\\_distinct)\ \ is the ratio of the number of genomic locations where exactly one read maps\ \ uniquely (M1) to the number of genomic locations where some reads map (M\\_distinct).\ \ A PBC1 value in the range 0 - 0.5 is severe bottlenecking, 0.5 - 0.8 is moderate\ \ bottlenecking, 0.8 - 0.9 is mild bottlenecking, and > 0.9 is no bottlenecking.\ \ PBC1 value > 0.9 is recommended, but > 0.8 is acceptable. ENCODE processed alignments\ \ file {ENCFF056GKK|/files/ENCFF056GKK/} processed by ChIP-seq ENCODE3 hg19 pipeline\ \ was generated from a library with PBC1 value of 0.84.\n\n**audit\\_warning**:\ \ PBC2 (PCR Bottlenecking Coefficient 2, M1/M2) is the ratio of the number of\ \ genomic locations where exactly one read maps uniquely (M1) to the number of\ \ genomic locations where two reads map uniquely (M2). A PBC2 value in the range\ \ 0 - 1 is severe bottlenecking, 1 - 3 is moderate bottlenecking, 3 - 10 is mild\ \ bottlenecking, > 10 is no bottlenecking. PBC2 value > 10 is recommended, but\ \ > 3 is acceptable. ENCODE processed alignments file {ENCFF056GKK|/files/ENCFF056GKK/}\ \ processed by ChIP-seq ENCODE3 hg19 pipeline was generated from a library with\ \ PBC2 value of 6.36.\n\n**audit\\_warning**: PBC1 (PCR Bottlenecking Coefficient\ \ 1, M1/M\\_distinct) is the ratio of the number of genomic locations where exactly\ \ one read maps uniquely (M1) to the number of genomic locations where some reads\ \ map (M\\_distinct). A PBC1 value in the range 0 - 0.5 is severe bottlenecking,\ \ 0.5 - 0.8 is moderate bottlenecking, 0.8 - 0.9 is mild bottlenecking, and >\ \ 0.9 is no bottlenecking. PBC1 value > 0.9 is recommended, but > 0.8 is acceptable.\ \ ENCODE processed alignments file {ENCFF052TDK|/files/ENCFF052TDK/} processed\ \ by ChIP-seq ENCODE3 hg19 pipeline was generated from a library with PBC1 value\ \ of 0.84.\n\n**audit\\_warning**: PBC2 (PCR Bottlenecking Coefficient 2, M1/M2)\ \ is the ratio of the number of genomic locations where exactly one read maps\ \ uniquely (M1) to the number of genomic locations where two reads map uniquely\ \ (M2). A PBC2 value in the range 0 - 1 is severe bottlenecking, 1 - 3 is moderate\ \ bottlenecking, 3 - 10 is mild bottlenecking, > 10 is no bottlenecking. PBC2\ \ value > 10 is recommended, but > 3 is acceptable. ENCODE processed alignments\ \ file {ENCFF052TDK|/files/ENCFF052TDK/} processed by ChIP-seq ENCODE3 hg19 pipeline\ \ was generated from a library with PBC2 value of 6.31.\n\n**audit\\_warning**:\ \ Replicate concordance in ChIP-seq experiments is measured by calculating IDR\ \ values (Irreproducible Discovery Rate). ENCODE processed IDR thresholded peaks\ \ files {ENCFF144JMY|/files/ENCFF144JMY/}, {ENCFF490QLA|/files/ENCFF490QLA/} processed\ \ by ChIP-seq ENCODE3 hg19 pipeline have a rescue ratio of 1.71 and a self consistency\ \ ratio of 3.05. According to ENCODE standards, having both rescue ratio and self\ \ consistency ratio values < 2 is recommended, but having only one of the ratio\ \ values < 2 is acceptable.\n\n**audit\\_warning**: Replicate concordance in ChIP-seq\ \ experiments is measured by calculating IDR values (Irreproducible Discovery\ \ Rate). ENCODE processed IDR thresholded peaks files {ENCFF270TGO|/files/ENCFF270TGO/},\ \ {ENCFF932EVL|/files/ENCFF932EVL/} processed by ChIP-seq ENCODE3 hg19 pipeline\ \ have a rescue ratio of 1.71 and a self consistency ratio of 3.05. According\ \ to ENCODE standards, having both rescue ratio and self consistency ratio values\ \ < 2 is recommended, but having only one of the ratio values < 2 is acceptable." labels: reference_genome: hg38/genomes/GRCh38-hg38 accession: ENCSR831EIW status: released assay_term_name: ChIP-seq simple_biosample_summary: '' biosample_summary: Homo sapiens HEK293T replication_type: isogenic biosample_ontology: /biosample-types/cell_line_EFO_0001184/ perturbed: false doi: 10.17989/ENCSR831EIW date_created: '2017-04-07T00:53:47.050047+00:00' date_released: '2017-04-14' submitter_comment: '' target: FOXM1