type: position_score table: filename: ENCFF075OIT.tabix.bed.gz header_mode: none zero_based: true format: tabix chrom: column_index: 0 pos_begin: column_index: 1 pos_end: column_index: 2 scores: - id: TF_ChIP-seq_ENCSR669NFS column_index: 3 type: float desc: signal histogram: type: number number_of_bins: 100 meta: summary: 'ChIP-seq ENCSR669NFS [TISSUE: Homo sapiens K562, TARGET: ARNT]' description: "**status**: released\n\n**biological\\_replicates**: Rep 3, Rep 4\n\ \n**summary**: \n\n**output\\_type**: IDR thresholded peaks\n\n**audit\\_internal\\\ _action**: Released analysis {ENCAN601LJH|/analyses/ENCAN601LJH/} has in progress\ \ subobject document {18b93594-86c1-4449-a073-dfb54406ec82|/documents/18b93594-86c1-4449-a073-dfb54406ec82/}\n\ \n**audit\\_internal\\_action**: Released analysis {ENCAN601LJH|/analyses/ENCAN601LJH/}\ \ has in progress subobject quality standard {encode4-tf-chip|/quality-standards/encode4-tf-chip/}\n\ \n**audit\\_warning**: Processed alignments file {ENCFF272TFI|/files/ENCFF272TFI/}\ \ processed by ChIP-seq ENCODE4 v1.6.1 GRCh38 pipeline has 17996124 usable fragments.\ \ The minimum ENCODE standard for each replicate in a ChIP-seq experiment targeting\ \ ARNT-human and investigated as a transcription factor is 10 million usable fragments.\ \ The recommended value is > 20 million, but > 10 million is acceptable. (See\ \ {ENCODE ChIP-seq data standards|/data-standards/chip-seq/} )\n\n**audit\\_warning**:\ \ Processed alignments file {ENCFF966JXF|/files/ENCFF966JXF/} processed by ChIP-seq\ \ ENCODE4 v1.6.1 GRCh38 pipeline has 19267129 usable fragments. The minimum ENCODE\ \ standard for each replicate in a ChIP-seq experiment targeting ARNT-human and\ \ investigated as a transcription factor is 10 million usable fragments. The recommended\ \ value is > 20 million, but > 10 million is acceptable. (See {ENCODE ChIP-seq\ \ data standards|/data-standards/chip-seq/} )\n\n**audit\\_warning**: PBC1 (PCR\ \ Bottlenecking Coefficient 1, M1/M\\_distinct) is the ratio of the number of\ \ genomic locations where exactly one read maps uniquely (M1) to the number of\ \ genomic locations where some reads map (M\\_distinct). A PBC1 value in the range\ \ 0 - 0.5 is severe bottlenecking, 0.5 - 0.8 is moderate bottlenecking, 0.8 -\ \ 0.9 is mild bottlenecking, and > 0.9 is no bottlenecking. PBC1 value > 0.9 is\ \ recommended, but > 0.8 is acceptable. ENCODE processed alignments file {ENCFF272TFI|/files/ENCFF272TFI/}\ \ processed by ChIP-seq ENCODE4 v1.6.1 GRCh38 pipeline was generated from a library\ \ with PBC1 value of 0.84.\n\n**audit\\_warning**: PBC2 (PCR Bottlenecking Coefficient\ \ 2, M1/M2) is the ratio of the number of genomic locations where exactly one\ \ read maps uniquely (M1) to the number of genomic locations where two reads map\ \ uniquely (M2). A PBC2 value in the range 0 - 1 is severe bottlenecking, 1 -\ \ 3 is moderate bottlenecking, 3 - 10 is mild bottlenecking, > 10 is no bottlenecking.\ \ PBC2 value > 10 is recommended, but > 3 is acceptable. ENCODE processed alignments\ \ file {ENCFF272TFI|/files/ENCFF272TFI/} processed by ChIP-seq ENCODE4 v1.6.1\ \ GRCh38 pipeline was generated from a library with PBC2 value of 6.19." labels: reference_genome: hg38/genomes/GRCh38-hg38 accession: ENCSR669NFS status: released assay_term_name: ChIP-seq simple_biosample_summary: '' biosample_summary: Homo sapiens K562 replication_type: isogenic biosample_ontology: /biosample-types/cell_line_EFO_0002067/ perturbed: false doi: 10.17989/ENCSR669NFS date_created: '2017-02-08T19:32:01.228685+00:00' date_released: '2018-01-26' submitter_comment: We note that this ChIP-seq experiment was performed using an antibody for which we have provided a compliant primary characterization but no secondary characterization. A secondary characterization using IP-MS was attempted, but the experiment failed. There is no remaining antibody from this lot number and therefore additional secondary characterizations cannot be attempted. However, because the replicate ChIP-seq datasets passed the ENCODE IDR ChIP-seq data quality standards, we are releasing the data to the public. target: ARNT