type: position_score table: filename: ENCFF380TJT.tabix.bed.gz header_mode: none zero_based: true format: tabix chrom: column_index: 0 pos_begin: column_index: 1 pos_end: column_index: 2 scores: - id: TF_ChIP-seq_ENCSR625ORP column_index: 3 type: float desc: signal histogram: type: number number_of_bins: 100 meta: summary: 'ChIP-seq ENCSR625ORP [TISSUE: Homo sapiens HepG2, TARGET: SYNCRIP]' description: "**status**: released\n\n**biological\\_replicates**: Rep 1, Rep 2\n\ \n**summary**: \n\n**output\\_type**: optimal IDR thresholded peaks\n\n**audit\\\ _internal\\_action**: Released analysis {ENCAN142PKL|/analyses/ENCAN142PKL/} has\ \ in progress subobject quality standard {encode3-tf-chip|/quality-standards/encode3-tf-chip/}\n\ \n**audit\\_not\\_compliant**: Processed alignments file {ENCFF880EQU|/files/ENCFF880EQU/}\ \ processed by ChIP-seq ENCODE3 hg19 pipeline has 9289767 usable fragments. The\ \ minimum ENCODE standard for each replicate in a ChIP-seq experiment targeting\ \ SYNCRIP-human and investigated as a transcription factor is 10 million usable\ \ fragments. The recommended value is > 20 million, but > 10 million is acceptable.\ \ (See {ENCODE ChIP-seq data standards|/data-standards/chip-seq/} )\n\n**audit\\\ _warning**: Processed alignments file {ENCFF221UBB|/files/ENCFF221UBB/} processed\ \ by ChIP-seq ENCODE3 hg19 pipeline has 11852754 usable fragments. The minimum\ \ ENCODE standard for each replicate in a ChIP-seq experiment targeting SYNCRIP-human\ \ and investigated as a transcription factor is 10 million usable fragments. The\ \ recommended value is > 20 million, but > 10 million is acceptable. (See {ENCODE\ \ ChIP-seq data standards|/data-standards/chip-seq/} )\n\n**audit\\_warning**:\ \ PBC1 (PCR Bottlenecking Coefficient 1, M1/M\\_distinct) is the ratio of the\ \ number of genomic locations where exactly one read maps uniquely (M1) to the\ \ number of genomic locations where some reads map (M\\_distinct). A PBC1 value\ \ in the range 0 - 0.5 is severe bottlenecking, 0.5 - 0.8 is moderate bottlenecking,\ \ 0.8 - 0.9 is mild bottlenecking, and > 0.9 is no bottlenecking. PBC1 value >\ \ 0.9 is recommended, but > 0.8 is acceptable. ENCODE processed alignments file\ \ {ENCFF880EQU|/files/ENCFF880EQU/} processed by ChIP-seq ENCODE3 hg19 pipeline\ \ was generated from a library with PBC1 value of 0.82.\n\n**audit\\_warning**:\ \ PBC2 (PCR Bottlenecking Coefficient 2, M1/M2) is the ratio of the number of\ \ genomic locations where exactly one read maps uniquely (M1) to the number of\ \ genomic locations where two reads map uniquely (M2). A PBC2 value in the range\ \ 0 - 1 is severe bottlenecking, 1 - 3 is moderate bottlenecking, 3 - 10 is mild\ \ bottlenecking, > 10 is no bottlenecking. PBC2 value > 10 is recommended, but\ \ > 3 is acceptable. ENCODE processed alignments file {ENCFF880EQU|/files/ENCFF880EQU/}\ \ processed by ChIP-seq ENCODE3 hg19 pipeline was generated from a library with\ \ PBC2 value of 5.60.\n\n**audit\\_warning**: PBC1 (PCR Bottlenecking Coefficient\ \ 1, M1/M\\_distinct) is the ratio of the number of genomic locations where exactly\ \ one read maps uniquely (M1) to the number of genomic locations where some reads\ \ map (M\\_distinct). A PBC1 value in the range 0 - 0.5 is severe bottlenecking,\ \ 0.5 - 0.8 is moderate bottlenecking, 0.8 - 0.9 is mild bottlenecking, and >\ \ 0.9 is no bottlenecking. PBC1 value > 0.9 is recommended, but > 0.8 is acceptable.\ \ ENCODE processed alignments file {ENCFF221UBB|/files/ENCFF221UBB/} processed\ \ by ChIP-seq ENCODE3 hg19 pipeline was generated from a library with PBC1 value\ \ of 0.87.\n\n**audit\\_warning**: PBC2 (PCR Bottlenecking Coefficient 2, M1/M2)\ \ is the ratio of the number of genomic locations where exactly one read maps\ \ uniquely (M1) to the number of genomic locations where two reads map uniquely\ \ (M2). A PBC2 value in the range 0 - 1 is severe bottlenecking, 1 - 3 is moderate\ \ bottlenecking, 3 - 10 is mild bottlenecking, > 10 is no bottlenecking. PBC2\ \ value > 10 is recommended, but > 3 is acceptable. ENCODE processed alignments\ \ file {ENCFF221UBB|/files/ENCFF221UBB/} processed by ChIP-seq ENCODE3 hg19 pipeline\ \ was generated from a library with PBC2 value of 7.49." labels: reference_genome: hg38/genomes/GRCh38-hg38 accession: ENCSR625ORP status: released assay_term_name: ChIP-seq simple_biosample_summary: '' biosample_summary: Homo sapiens HepG2 replication_type: isogenic biosample_ontology: /biosample-types/cell_line_EFO_0001187/ perturbed: false doi: 10.17989/ENCSR625ORP date_created: '2014-11-27T18:20:30.767289+00:00' date_released: '2018-05-16' submitter_comment: '' target: SYNCRIP