type: position_score table: filename: ENCFF675SAG.tabix.bed.gz header_mode: none zero_based: true format: tabix chrom: column_index: 0 pos_begin: column_index: 1 pos_end: column_index: 2 scores: - id: TF_ChIP-seq_ENCSR419ODQ column_index: 3 type: float desc: 'TF_ChIP-seq ENCSR419ODQ [biosample_summary="Homo sapiens MCF-7" and target="ZNF507"]' histogram: type: number number_of_bins: 100 meta: summary: 'TF_ChIP-seq ENCSR419ODQ [biosample_summary="Homo sapiens MCF-7" and target="ZNF507"]' description: "**status**: released\n\n**biological\\_replicates**: Rep 1, Rep 2\n\ \n**summary**: \n\n**output\\_type**: optimal IDR thresholded peaks\n\n**audit\\\ _internal\\_action**: Archived analysis {ENCAN922GIY|/analyses/ENCAN922GIY/} has\ \ in progress subobject quality standard {encode3-tf-chip|/quality-standards/encode3-tf-chip/}\n\ \n**audit\\_internal\\_action**: File {ENCFF675SAG|/files/ENCFF675SAG/} with status\ \ 'released' is derived from file {ENCFF419RSJ|/files/ENCFF419RSJ/} with status\ \ 'archived'.\n\n**audit\\_not\\_compliant**: NRF (Non Redundant Fraction) is\ \ equal to the result of the division of the number of reads after duplicates\ \ removal by the total number of reads. An NRF value in the range 0 - 0.5 is poor\ \ complexity, 0.5 - 0.8 is moderate complexity, and > 0.8 high complexity. NRF\ \ value > 0.8 is recommended, but > 0.5 is acceptable. ENCODE processed alignments\ \ file {ENCFF742OPD|/files/ENCFF742OPD/} processed by ChIP-seq ENCODE3 GRCh38\ \ pipeline was generated from a library with NRF value of 0.28.\n\n**audit\\_not\\\ _compliant**: PBC1 (PCR Bottlenecking Coefficient 1, M1/M\\_distinct) is the ratio\ \ of the number of genomic locations where exactly one read maps uniquely (M1)\ \ to the number of genomic locations where some reads map (M\\_distinct). A PBC1\ \ value in the range 0 - 0.5 is severe bottlenecking, 0.5 - 0.8 is moderate bottlenecking,\ \ 0.8 - 0.9 is mild bottlenecking, and > 0.9 is no bottlenecking. PBC1 value >\ \ 0.9 is recommended, but > 0.8 is acceptable. ENCODE processed alignments file\ \ {ENCFF742OPD|/files/ENCFF742OPD/} processed by ChIP-seq ENCODE3 GRCh38 pipeline\ \ was generated from a library with PBC1 value of 0.30.\n\n**audit\\_warning**:\ \ Processed alignments file {ENCFF742OPD|/files/ENCFF742OPD/} processed by ChIP-seq\ \ ENCODE3 GRCh38 pipeline has 10824215 usable fragments. The minimum ENCODE standard\ \ for each replicate in a ChIP-seq experiment targeting ZNF507-human and investigated\ \ as a transcription factor is 10 million usable fragments. The recommended value\ \ is > 20 million, but > 10 million is acceptable. (See {ENCODE ChIP-seq data\ \ standards|/data-standards/chip-seq/} )\n\n**audit\\_warning**: PBC2 (PCR Bottlenecking\ \ Coefficient 2, M1/M2) is the ratio of the number of genomic locations where\ \ exactly one read maps uniquely (M1) to the number of genomic locations where\ \ two reads map uniquely (M2). A PBC2 value in the range 0 - 1 is severe bottlenecking,\ \ 1 - 3 is moderate bottlenecking, 3 - 10 is mild bottlenecking, > 10 is no bottlenecking.\ \ PBC2 value > 10 is recommended, but > 3 is acceptable. ENCODE processed alignments\ \ file {ENCFF742OPD|/files/ENCFF742OPD/} processed by ChIP-seq ENCODE3 GRCh38\ \ pipeline was generated from a library with PBC2 value of 1.53." labels: reference_genome: hg38/genomes/GRCh38-hg38 accession: ENCSR419ODQ status: released assay_term_name: ChIP-seq simple_biosample_summary: '' biosample_summary: Homo sapiens MCF-7 replication_type: isogenic biosample_ontology: /biosample-types/cell_line_EFO_0001203/ perturbed: false doi: 10.17989/ENCSR419ODQ date_created: '2016-04-28T23:02:15.610485+00:00' date_released: '2018-01-26' submitter_comment: We note that this ChIP-seq experiment was performed using an antibody for which we have provided a compliant primary characterization but no secondary characterization. A secondary characterization using IP-MS was attempted, but the experiment failed. There is no remaining antibody from this lot number and therefore additional secondary characterizations cannot be attempted. However, because the replicate ChIP-seq datasets passed the ENCODE IDR ChIP-seq data quality standards, we are releasing the data to the public. target: ZNF507