type: position_score table: filename: ENCFF089GNH.tabix.bed.gz header_mode: none zero_based: true format: tabix chrom: column_index: 0 pos_begin: column_index: 1 pos_end: column_index: 2 scores: - id: TF_ChIP-seq_ENCSR330ADN column_index: 3 type: float desc: signal histogram: type: number number_of_bins: 100 meta: summary: 'ChIP-seq ENCSR330ADN [TISSUE: Homo sapiens MCF-7, TARGET: DDX20]' description: "**status**: released\n\n**biological\\_replicates**: Rep 1, Rep 2\n\ \n**summary**: \n\n**output\\_type**: optimal IDR thresholded peaks\n\n**audit\\\ _internal\\_action**: Archived analysis {ENCAN170AXU|/analyses/ENCAN170AXU/} has\ \ in progress subobject quality standard {encode3-tf-chip|/quality-standards/encode3-tf-chip/}\n\ \n**audit\\_internal\\_action**: File {ENCFF089GNH|/files/ENCFF089GNH/} with status\ \ 'released' is derived from file {ENCFF419RSJ|/files/ENCFF419RSJ/} with status\ \ 'archived'.\n\n**audit\\_warning**: PBC1 (PCR Bottlenecking Coefficient 1, M1/M\\\ _distinct) is the ratio of the number of genomic locations where exactly one read\ \ maps uniquely (M1) to the number of genomic locations where some reads map (M\\\ _distinct). A PBC1 value in the range 0 - 0.5 is severe bottlenecking, 0.5 - 0.8\ \ is moderate bottlenecking, 0.8 - 0.9 is mild bottlenecking, and > 0.9 is no\ \ bottlenecking. PBC1 value > 0.9 is recommended, but > 0.8 is acceptable. ENCODE\ \ processed alignments file {ENCFF682IXJ|/files/ENCFF682IXJ/} processed by ChIP-seq\ \ ENCODE3 GRCh38 pipeline was generated from a library with PBC1 value of 0.86.\n\ \n**audit\\_warning**: PBC2 (PCR Bottlenecking Coefficient 2, M1/M2) is the ratio\ \ of the number of genomic locations where exactly one read maps uniquely (M1)\ \ to the number of genomic locations where two reads map uniquely (M2). A PBC2\ \ value in the range 0 - 1 is severe bottlenecking, 1 - 3 is moderate bottlenecking,\ \ 3 - 10 is mild bottlenecking, > 10 is no bottlenecking. PBC2 value > 10 is recommended,\ \ but > 3 is acceptable. ENCODE processed alignments file {ENCFF682IXJ|/files/ENCFF682IXJ/}\ \ processed by ChIP-seq ENCODE3 GRCh38 pipeline was generated from a library with\ \ PBC2 value of 6.83.\n\n**audit\\_warning**: Replicate concordance in ChIP-seq\ \ experiments is measured by calculating IDR values (Irreproducible Discovery\ \ Rate). ENCODE processed IDR thresholded peaks files {ENCFF089GNH|/files/ENCFF089GNH/},\ \ {ENCFF558FCT|/files/ENCFF558FCT/} processed by ChIP-seq ENCODE3 GRCh38 pipeline\ \ have a rescue ratio of 1.62 and a self consistency ratio of 2.17. According\ \ to ENCODE standards, having both rescue ratio and self consistency ratio values\ \ < 2 is recommended, but having only one of the ratio values < 2 is acceptable.\n\ \n**audit\\_warning**: Replicate concordance in ChIP-seq experiments is measured\ \ by calculating IDR values (Irreproducible Discovery Rate). ENCODE processed\ \ IDR thresholded peaks files {ENCFF199QUM|/files/ENCFF199QUM/}, {ENCFF406DTF|/files/ENCFF406DTF/}\ \ processed by ChIP-seq ENCODE3 GRCh38 pipeline have a rescue ratio of 1.62 and\ \ a self consistency ratio of 2.17. According to ENCODE standards, having both\ \ rescue ratio and self consistency ratio values < 2 is recommended, but having\ \ only one of the ratio values < 2 is acceptable." labels: reference_genome: hg38/genomes/GRCh38-hg38 accession: ENCSR330ADN status: released assay_term_name: ChIP-seq simple_biosample_summary: '' biosample_summary: Homo sapiens MCF-7 replication_type: isogenic biosample_ontology: /biosample-types/cell_line_EFO_0001203/ perturbed: false doi: 10.17989/ENCSR330ADN date_created: '2017-06-09T20:27:43.401999+00:00' date_released: '2017-06-29' submitter_comment: '' target: DDX20