type: position_score
table:
  filename: ENCFF625WYP.tabix.bed.gz
  header_mode: none
  zero_based: true
  format: tabix
  chrom:
    column_index: 0
  pos_begin:
    column_index: 1
  pos_end:
    column_index: 2
scores:
- id: TF_ChIP-seq_ENCSR180MUU
  column_index: 3
  type: float
  desc: signal
  histogram:
    type: number
    number_of_bins: 100
meta:
  summary: 'ChIP-seq ENCSR180MUU [TISSUE: Homo sapiens HepG2 genetically modified
    (insertion) using CRISPR targeting H. sapiens RREB1, TARGET: RREB1]'
  description: '**status**: released


    **biological\_replicates**: Rep 1, Rep 2


    **summary**: genetically modified (insertion) using CRISPR targeting H. sapiens
    RREB1


    **output\_type**: IDR thresholded peaks


    **audit\_internal\_action**: Released analysis {ENCAN803KGM|/analyses/ENCAN803KGM/}
    has in progress subobject quality standard {encode4-tf-chip|/quality-standards/encode4-tf-chip/}


    **audit\_internal\_action**: Released analysis {ENCAN803KGM|/analyses/ENCAN803KGM/}
    has in progress subobject document {1b4d5902-0972-42d3-aabd-75fa51fc0fcb|/documents/1b4d5902-0972-42d3-aabd-75fa51fc0fcb/}


    **audit\_warning**: Replicate concordance in ChIP-seq experiments is measured
    by calculating IDR values (Irreproducible Discovery Rate). ENCODE processed IDR
    thresholded peaks files {ENCFF625WYP|/files/ENCFF625WYP/} processed by ChIP-seq
    ENCODE4 v1.5.1 GRCh38 pipeline have a rescue ratio of 1.48 and a self consistency
    ratio of 4.33. According to ENCODE standards, having both rescue ratio and self
    consistency ratio values < 2 is recommended, but having only one of the ratio
    values < 2 is acceptable.


    **audit\_warning**: Replicate concordance in ChIP-seq experiments is measured
    by calculating IDR values (Irreproducible Discovery Rate). ENCODE processed IDR
    thresholded peaks files {ENCFF986CSN|/files/ENCFF986CSN/} processed by ChIP-seq
    ENCODE4 v1.5.1 GRCh38 pipeline have a rescue ratio of 1.48 and a self consistency
    ratio of 4.33. According to ENCODE standards, having both rescue ratio and self
    consistency ratio values < 2 is recommended, but having only one of the ratio
    values < 2 is acceptable.'
  labels:
    reference_genome: hg38/genomes/GRCh38-hg38
    accession: ENCSR180MUU
    status: released
    assay_term_name: ChIP-seq
    simple_biosample_summary: genetically modified (insertion) using CRISPR targeting
      H. sapiens RREB1
    biosample_summary: Homo sapiens HepG2 genetically modified (insertion) using CRISPR
      targeting H. sapiens RREB1
    replication_type: isogenic
    biosample_ontology: /biosample-types/cell_line_EFO_0001187/
    perturbed: false
    doi: 10.17989/ENCSR180MUU
    date_created: '2018-03-07T15:43:34.565495+00:00'
    date_released: '2020-08-28'
    submitter_comment: ''
    target: RREB1