type: position_score table: filename: ENCFF706LIT.tabix.bed.gz header_mode: none zero_based: true format: tabix chrom: column_index: 0 pos_begin: column_index: 1 pos_end: column_index: 2 scores: - id: TF_ChIP-seq_ENCSR107RHZ column_index: 3 type: float desc: signal histogram: type: number number_of_bins: 100 meta: summary: 'ChIP-seq ENCSR107RHZ [TISSUE: Homo sapiens K562, TARGET: YBX1]' description: "**status**: released\n\n**biological\\_replicates**: Rep 1, Rep 2\n\ \n**summary**: \n\n**output\\_type**: optimal IDR thresholded peaks\n\n**audit\\\ _internal\\_action**: Archived analysis {ENCAN404OEI|/analyses/ENCAN404OEI/} has\ \ in progress subobject quality standard {encode3-tf-chip|/quality-standards/encode3-tf-chip/}\n\ \n**audit\\_warning**: PBC1 (PCR Bottlenecking Coefficient 1, M1/M\\_distinct)\ \ is the ratio of the number of genomic locations where exactly one read maps\ \ uniquely (M1) to the number of genomic locations where some reads map (M\\_distinct).\ \ A PBC1 value in the range 0 - 0.5 is severe bottlenecking, 0.5 - 0.8 is moderate\ \ bottlenecking, 0.8 - 0.9 is mild bottlenecking, and > 0.9 is no bottlenecking.\ \ PBC1 value > 0.9 is recommended, but > 0.8 is acceptable. ENCODE processed alignments\ \ file {ENCFF869CLO|/files/ENCFF869CLO/} processed by ChIP-seq ENCODE3 hg19 pipeline\ \ was generated from a library with PBC1 value of 0.88.\n\n**audit\\_warning**:\ \ PBC2 (PCR Bottlenecking Coefficient 2, M1/M2) is the ratio of the number of\ \ genomic locations where exactly one read maps uniquely (M1) to the number of\ \ genomic locations where two reads map uniquely (M2). A PBC2 value in the range\ \ 0 - 1 is severe bottlenecking, 1 - 3 is moderate bottlenecking, 3 - 10 is mild\ \ bottlenecking, > 10 is no bottlenecking. PBC2 value > 10 is recommended, but\ \ > 3 is acceptable. ENCODE processed alignments file {ENCFF869CLO|/files/ENCFF869CLO/}\ \ processed by ChIP-seq ENCODE3 hg19 pipeline was generated from a library with\ \ PBC2 value of 8.02.\n\n**audit\\_warning**: Replicate concordance in ChIP-seq\ \ experiments is measured by calculating IDR values (Irreproducible Discovery\ \ Rate). ENCODE processed IDR thresholded peaks files {ENCFF452VYJ|/files/ENCFF452VYJ/},\ \ {ENCFF706LIT|/files/ENCFF706LIT/} processed by ChIP-seq ENCODE3 hg19 pipeline\ \ have a rescue ratio of 2.80 and a self consistency ratio of 1.11. According\ \ to ENCODE standards, having both rescue ratio and self consistency ratio values\ \ < 2 is recommended, but having only one of the ratio values < 2 is acceptable.\n\ \n**audit\\_warning**: Replicate concordance in ChIP-seq experiments is measured\ \ by calculating IDR values (Irreproducible Discovery Rate). ENCODE processed\ \ IDR thresholded peaks files {ENCFF015BVQ|/files/ENCFF015BVQ/}, {ENCFF876GPT|/files/ENCFF876GPT/}\ \ processed by ChIP-seq ENCODE3 hg19 pipeline have a rescue ratio of 2.80 and\ \ a self consistency ratio of 1.11. According to ENCODE standards, having both\ \ rescue ratio and self consistency ratio values < 2 is recommended, but having\ \ only one of the ratio values < 2 is acceptable." labels: reference_genome: hg38/genomes/GRCh38-hg38 accession: ENCSR107RHZ status: released assay_term_name: ChIP-seq simple_biosample_summary: '' biosample_summary: Homo sapiens K562 replication_type: isogenic biosample_ontology: /biosample-types/cell_line_EFO_0002067/ perturbed: false doi: 10.17989/ENCSR107RHZ date_created: '2014-12-18T04:06:47.796310+00:00' date_released: '2016-07-28' submitter_comment: '' target: YBX1