type: position_score
table:
  filename: ENCFF736NYC.tabix.bed.gz
  header_mode: none
  zero_based: true
  format: tabix
  chrom:
    column_index: 0
  pos_begin:
    column_index: 1
  pos_end:
    column_index: 2
scores:
- id: TF_ChIP-seq_ENCSR000DWE
  column_index: 3
  type: float
  desc: 'TF_ChIP-seq ENCSR000DWE [biosample_summary="Homo sapiens K562" and target="CTCF"]'
  histogram:
    type: number
    number_of_bins: 100
meta:
  summary: 'TF_ChIP-seq ENCSR000DWE [biosample_summary="Homo sapiens K562" and target="CTCF"]'
  description: "**status**: released\n\n**biological\\_replicates**: Rep 1, Rep 2\n\
    \n**summary**: \n\n**output\\_type**: IDR thresholded peaks\n\n**audit\\_internal\\\
    _action**: Released analysis {ENCAN088YDV|/analyses/ENCAN088YDV/} has in progress\
    \ subobject quality standard {encode4-tf-chip|/quality-standards/encode4-tf-chip/}\n\
    \n**audit\\_internal\\_action**: Released analysis {ENCAN088YDV|/analyses/ENCAN088YDV/}\
    \ has in progress subobject document {28fff1e5-ee00-4bcb-bb6f-d4fd1b7ebde8|/documents/28fff1e5-ee00-4bcb-bb6f-d4fd1b7ebde8/}\n\
    \n**audit\\_not\\_compliant**: Processed alignments file {ENCFF196QVZ|/files/ENCFF196QVZ/}\
    \ processed by ChIP-seq ENCODE4 v1.5.1 GRCh38 pipeline has 6050973 usable fragments.\
    \ The minimum ENCODE standard for each replicate in a ChIP-seq experiment targeting\
    \ CTCF-human and investigated as a transcription factor is 10 million usable fragments.\
    \ The recommended value is > 20 million, but > 10 million is acceptable. (See\
    \ {ENCODE ChIP-seq data standards|/data-standards/chip-seq/} )\n\n**audit\\_not\\\
    _compliant**: NRF (Non Redundant Fraction) is equal to the result of the division\
    \ of the number of reads after duplicates removal by the total number of reads.\
    \ An NRF value in the range 0 - 0.5 is poor complexity, 0.5 - 0.8 is moderate\
    \ complexity, and > 0.8 high complexity. NRF value > 0.8 is recommended, but >\
    \ 0.5 is acceptable. ENCODE processed alignments file {ENCFF196QVZ|/files/ENCFF196QVZ/}\
    \ processed by ChIP-seq ENCODE4 v1.5.1 GRCh38 pipeline was generated from a library\
    \ with NRF value of 0.47.\n\n**audit\\_not\\_compliant**: PBC1 (PCR Bottlenecking\
    \ Coefficient 1, M1/M\\_distinct) is the ratio of the number of genomic locations\
    \ where exactly one read maps uniquely (M1) to the number of genomic locations\
    \ where some reads map (M\\_distinct). A PBC1 value in the range 0 - 0.5 is severe\
    \ bottlenecking, 0.5 - 0.8 is moderate bottlenecking, 0.8 - 0.9 is mild bottlenecking,\
    \ and > 0.9 is no bottlenecking. PBC1 value > 0.9 is recommended, but > 0.8 is\
    \ acceptable. ENCODE processed alignments file {ENCFF196QVZ|/files/ENCFF196QVZ/}\
    \ processed by ChIP-seq ENCODE4 v1.5.1 GRCh38 pipeline was generated from a library\
    \ with PBC1 value of 0.41.\n\n**audit\\_warning**: Processed alignments file {ENCFF800GVR|/files/ENCFF800GVR/}\
    \ processed by ChIP-seq ENCODE4 v1.5.1 GRCh38 pipeline has 13822467 usable fragments.\
    \ The minimum ENCODE standard for each replicate in a ChIP-seq experiment targeting\
    \ CTCF-human and investigated as a transcription factor is 10 million usable fragments.\
    \ The recommended value is > 20 million, but > 10 million is acceptable. (See\
    \ {ENCODE ChIP-seq data standards|/data-standards/chip-seq/} )\n\n**audit\\_warning**:\
    \ PBC2 (PCR Bottlenecking Coefficient 2, M1/M2) is the ratio of the number of\
    \ genomic locations where exactly one read maps uniquely (M1) to the number of\
    \ genomic locations where two reads map uniquely (M2). A PBC2 value in the range\
    \ 0 - 1 is severe bottlenecking, 1 - 3 is moderate bottlenecking, 3 - 10 is mild\
    \ bottlenecking, > 10 is no bottlenecking. PBC2 value > 10 is recommended, but\
    \ > 3 is acceptable. ENCODE processed alignments file {ENCFF196QVZ|/files/ENCFF196QVZ/}\
    \ processed by ChIP-seq ENCODE4 v1.5.1 GRCh38 pipeline was generated from a library\
    \ with PBC2 value of 1.41."
  labels:
    reference_genome: hg38/genomes/GRCh38-hg38
    accession: ENCSR000DWE
    status: released
    assay_term_name: ChIP-seq
    simple_biosample_summary: ''
    biosample_summary: Homo sapiens K562
    replication_type: isogenic
    biosample_ontology: /biosample-types/cell_line_EFO_0002067/
    perturbed: false
    doi: 10.17989/ENCSR000DWE
    date_created: '2014-02-12T22:47:45.105782+00:00'
    date_released: '2011-03-17'
    submitter_comment: Replicate 1,1 of this experiment was previously attributed
      to biosample ENCBS698AAA and replicate 2,1 of this experiment was previously
      attributed to biosample ENCBS698AAA but they have since been corrected to the
      current biosamples. Please note that the biosample term has remain unchanged.
    target: CTCF