type: position_score
table:
  filename: ENCFF951PEM.tabix.bed.gz
  header_mode: none
  zero_based: true
  format: tabix
  chrom:
    column_index: 0
  pos_begin:
    column_index: 1
  pos_end:
    column_index: 2
scores:
- id: TF_ChIP-seq_ENCSR000DRZ
  column_index: 3
  type: float
  desc: signal
  histogram:
    type: number
    number_of_bins: 100
meta:
  summary: 'ChIP-seq ENCSR000DRZ [TISSUE: Homo sapiens GM12878, TARGET: CTCF]'
  description: "**status**: released\n\n**biological\\_replicates**: Rep 1, Rep 2\n\
    \n**summary**: \n\n**output\\_type**: IDR thresholded peaks\n\n**audit\\_error**:\
    \ Processed alignments file {ENCFF430XCG|/files/ENCFF430XCG/} processed by ChIP-seq\
    \ ENCODE4 v1.5.1 GRCh38 pipeline has 4542118 usable fragments. The minimum ENCODE\
    \ standard for each replicate in a ChIP-seq experiment targeting CTCF-human and\
    \ investigated as a transcription factor is 10 million usable fragments. The recommended\
    \ value is > 20 million, but > 10 million is acceptable. (See {ENCODE ChIP-seq\
    \ data standards|/data-standards/chip-seq/} )\n\n**audit\\_internal\\_action**:\
    \ Released analysis {ENCAN164VUO|/analyses/ENCAN164VUO/} has in progress subobject\
    \ quality standard {encode4-tf-chip|/quality-standards/encode4-tf-chip/}\n\n**audit\\\
    _internal\\_action**: Released analysis {ENCAN164VUO|/analyses/ENCAN164VUO/} has\
    \ in progress subobject document {1494e1a1-d2eb-4337-804b-ea9179502fab|/documents/1494e1a1-d2eb-4337-804b-ea9179502fab/}\n\
    \n**audit\\_warning**: Processed alignments file {ENCFF794BPW|/files/ENCFF794BPW/}\
    \ processed by ChIP-seq ENCODE4 v1.5.1 GRCh38 pipeline has 14735031 usable fragments.\
    \ The minimum ENCODE standard for each replicate in a ChIP-seq experiment targeting\
    \ CTCF-human and investigated as a transcription factor is 10 million usable fragments.\
    \ The recommended value is > 20 million, but > 10 million is acceptable. (See\
    \ {ENCODE ChIP-seq data standards|/data-standards/chip-seq/} )\n\n**audit\\_warning**:\
    \ NRF (Non Redundant Fraction) is equal to the result of the division of the number\
    \ of reads after duplicates removal by the total number of reads. An NRF value\
    \ in the range 0 - 0.5 is poor complexity, 0.5 - 0.8 is moderate complexity, and\
    \ > 0.8 high complexity. NRF value > 0.8 is recommended, but > 0.5 is acceptable.\
    \ ENCODE processed alignments file {ENCFF430XCG|/files/ENCFF430XCG/} processed\
    \ by ChIP-seq ENCODE4 v1.5.1 GRCh38 pipeline was generated from a library with\
    \ NRF value of 0.64.\n\n**audit\\_warning**: PBC1 (PCR Bottlenecking Coefficient\
    \ 1, M1/M\\_distinct) is the ratio of the number of genomic locations where exactly\
    \ one read maps uniquely (M1) to the number of genomic locations where some reads\
    \ map (M\\_distinct). A PBC1 value in the range 0 - 0.5 is severe bottlenecking,\
    \ 0.5 - 0.8 is moderate bottlenecking, 0.8 - 0.9 is mild bottlenecking, and >\
    \ 0.9 is no bottlenecking. PBC1 value > 0.9 is recommended, but > 0.8 is acceptable.\
    \ ENCODE processed alignments file {ENCFF430XCG|/files/ENCFF430XCG/} processed\
    \ by ChIP-seq ENCODE4 v1.5.1 GRCh38 pipeline was generated from a library with\
    \ PBC1 value of 0.61.\n\n**audit\\_warning**: PBC2 (PCR Bottlenecking Coefficient\
    \ 2, M1/M2) is the ratio of the number of genomic locations where exactly one\
    \ read maps uniquely (M1) to the number of genomic locations where two reads map\
    \ uniquely (M2). A PBC2 value in the range 0 - 1 is severe bottlenecking, 1 -\
    \ 3 is moderate bottlenecking, 3 - 10 is mild bottlenecking, > 10 is no bottlenecking.\
    \ PBC2 value > 10 is recommended, but > 3 is acceptable. ENCODE processed alignments\
    \ file {ENCFF430XCG|/files/ENCFF430XCG/} processed by ChIP-seq ENCODE4 v1.5.1\
    \ GRCh38 pipeline was generated from a library with PBC2 value of 2.30."
  labels:
    reference_genome: hg38/genomes/GRCh38-hg38
    accession: ENCSR000DRZ
    status: released
    assay_term_name: ChIP-seq
    simple_biosample_summary: ''
    biosample_summary: Homo sapiens GM12878
    replication_type: isogenic
    biosample_ontology: /biosample-types/cell_line_EFO_0002784/
    perturbed: false
    doi: 10.17989/ENCSR000DRZ
    date_created: '2014-02-12T22:41:06.575390+00:00'
    date_released: '2011-03-17'
    submitter_comment: Replicate 2,1 of this experiment was previously attributed
      to biosample ENCBS195XMM and replicate 1,1 of this experiment was previously
      attributed to biosample ENCBS195XMM but they have since been corrected to the
      current biosamples. Please note that the biosample term has remain unchanged.
    target: CTCF