type: position_score table: filename: ENCFF910AWG.tabix.bed.gz header_mode: none zero_based: true format: tabix chrom: column_index: 0 pos_begin: column_index: 1 pos_end: column_index: 2 scores: - id: TF_ChIP-seq_ENCSR000DRR column_index: 3 type: float desc: signal histogram: type: number number_of_bins: 100 meta: summary: 'ChIP-seq ENCSR000DRR [TISSUE: Homo sapiens GM12874, TARGET: CTCF]' description: "**status**: released\n\n**biological\\_replicates**: Rep 1, Rep 2\n\ \n**summary**: \n\n**output\\_type**: IDR thresholded peaks\n\n**audit\\_internal\\\ _action**: Released analysis {ENCAN623KGJ|/analyses/ENCAN623KGJ/} has in progress\ \ subobject document {1818faa7-0ba6-44d0-91fa-609065b39564|/documents/1818faa7-0ba6-44d0-91fa-609065b39564/}\n\ \n**audit\\_internal\\_action**: Released analysis {ENCAN623KGJ|/analyses/ENCAN623KGJ/}\ \ has in progress subobject quality standard {encode4-tf-chip|/quality-standards/encode4-tf-chip/}\n\ \n**audit\\_not\\_compliant**: Processed alignments file {ENCFF876DFJ|/files/ENCFF876DFJ/}\ \ processed by ChIP-seq ENCODE4 v1.5.1 GRCh38 pipeline has 6053773 usable fragments.\ \ The minimum ENCODE standard for each replicate in a ChIP-seq experiment targeting\ \ CTCF-human and investigated as a transcription factor is 10 million usable fragments.\ \ The recommended value is > 20 million, but > 10 million is acceptable. (See\ \ {ENCODE ChIP-seq data standards|/data-standards/chip-seq/} )\n\n**audit\\_warning**:\ \ Processed alignments file {ENCFF231YCS|/files/ENCFF231YCS/} processed by ChIP-seq\ \ ENCODE4 v1.5.1 GRCh38 pipeline has 10313505 usable fragments. The minimum ENCODE\ \ standard for each replicate in a ChIP-seq experiment targeting CTCF-human and\ \ investigated as a transcription factor is 10 million usable fragments. The recommended\ \ value is > 20 million, but > 10 million is acceptable. (See {ENCODE ChIP-seq\ \ data standards|/data-standards/chip-seq/} )\n\n**audit\\_warning**: NRF (Non\ \ Redundant Fraction) is equal to the result of the division of the number of\ \ reads after duplicates removal by the total number of reads. An NRF value in\ \ the range 0 - 0.5 is poor complexity, 0.5 - 0.8 is moderate complexity, and\ \ > 0.8 high complexity. NRF value > 0.8 is recommended, but > 0.5 is acceptable.\ \ ENCODE processed alignments file {ENCFF876DFJ|/files/ENCFF876DFJ/} processed\ \ by ChIP-seq ENCODE4 v1.5.1 GRCh38 pipeline was generated from a library with\ \ NRF value of 0.55.\n\n**audit\\_warning**: PBC1 (PCR Bottlenecking Coefficient\ \ 1, M1/M\\_distinct) is the ratio of the number of genomic locations where exactly\ \ one read maps uniquely (M1) to the number of genomic locations where some reads\ \ map (M\\_distinct). A PBC1 value in the range 0 - 0.5 is severe bottlenecking,\ \ 0.5 - 0.8 is moderate bottlenecking, 0.8 - 0.9 is mild bottlenecking, and >\ \ 0.9 is no bottlenecking. PBC1 value > 0.9 is recommended, but > 0.8 is acceptable.\ \ ENCODE processed alignments file {ENCFF876DFJ|/files/ENCFF876DFJ/} processed\ \ by ChIP-seq ENCODE4 v1.5.1 GRCh38 pipeline was generated from a library with\ \ PBC1 value of 0.52.\n\n**audit\\_warning**: PBC2 (PCR Bottlenecking Coefficient\ \ 2, M1/M2) is the ratio of the number of genomic locations where exactly one\ \ read maps uniquely (M1) to the number of genomic locations where two reads map\ \ uniquely (M2). A PBC2 value in the range 0 - 1 is severe bottlenecking, 1 -\ \ 3 is moderate bottlenecking, 3 - 10 is mild bottlenecking, > 10 is no bottlenecking.\ \ PBC2 value > 10 is recommended, but > 3 is acceptable. ENCODE processed alignments\ \ file {ENCFF876DFJ|/files/ENCFF876DFJ/} processed by ChIP-seq ENCODE4 v1.5.1\ \ GRCh38 pipeline was generated from a library with PBC2 value of 1.92." labels: reference_genome: hg38/genomes/GRCh38-hg38 accession: ENCSR000DRR status: released assay_term_name: ChIP-seq simple_biosample_summary: '' biosample_summary: Homo sapiens GM12874 replication_type: isogenic biosample_ontology: /biosample-types/cell_line_EFO_0001161/ perturbed: false doi: 10.17989/ENCSR000DRR date_created: '2013-12-12T06:56:54.748972+00:00' date_released: '2011-03-17' submitter_comment: Replicate 1,1 of this experiment was previously attributed to biosample ENCBS218AAA but it has since been corrected to the current biosample. Please note that the biosample term has remain unchanged. target: CTCF