type: position_score table: filename: ENCFF119XBW.tabix.bed.gz header_mode: none zero_based: true format: tabix chrom: column_index: 0 pos_begin: column_index: 1 pos_end: column_index: 2 scores: - id: TF_ChIP-seq_ENCSR000DPS column_index: 3 type: float desc: signal histogram: type: number number_of_bins: 100 meta: summary: 'ChIP-seq ENCSR000DPS [TISSUE: Homo sapiens AG09319, TARGET: CTCF]' description: "**status**: released\n\n**biological\\_replicates**: Rep 1, Rep 2\n\ \n**summary**: \n\n**output\\_type**: optimal IDR thresholded peaks\n\n**audit\\\ _internal\\_action**: File {ENCFF119XBW|/files/ENCFF119XBW/} with status 'released'\ \ is derived from file {ENCFF419RSJ|/files/ENCFF419RSJ/} with status 'archived'.\n\ \n**audit\\_internal\\_action**: Archived analysis {ENCAN038AZV|/analyses/ENCAN038AZV/}\ \ has in progress subobject quality standard {encode3-tf-chip|/quality-standards/encode3-tf-chip/}\n\ \n**audit\\_warning**: Processed alignments file {ENCFF278LWC|/files/ENCFF278LWC/}\ \ processed by ChIP-seq ENCODE3 GRCh38 pipeline has 16344332 usable fragments.\ \ The minimum ENCODE standard for each replicate in a ChIP-seq experiment targeting\ \ CTCF-human and investigated as a transcription factor is 10 million usable fragments.\ \ The recommended value is > 20 million, but > 10 million is acceptable. (See\ \ {ENCODE ChIP-seq data standards|/data-standards/chip-seq/} )\n\n**audit\\_warning**:\ \ NRF (Non Redundant Fraction) is equal to the result of the division of the number\ \ of reads after duplicates removal by the total number of reads. An NRF value\ \ in the range 0 - 0.5 is poor complexity, 0.5 - 0.8 is moderate complexity, and\ \ > 0.8 high complexity. NRF value > 0.8 is recommended, but > 0.5 is acceptable.\ \ ENCODE processed alignments file {ENCFF278LWC|/files/ENCFF278LWC/} processed\ \ by ChIP-seq ENCODE3 GRCh38 pipeline was generated from a library with NRF value\ \ of 0.78.\n\n**audit\\_warning**: PBC1 (PCR Bottlenecking Coefficient 1, M1/M\\\ _distinct) is the ratio of the number of genomic locations where exactly one read\ \ maps uniquely (M1) to the number of genomic locations where some reads map (M\\\ _distinct). A PBC1 value in the range 0 - 0.5 is severe bottlenecking, 0.5 - 0.8\ \ is moderate bottlenecking, 0.8 - 0.9 is mild bottlenecking, and > 0.9 is no\ \ bottlenecking. PBC1 value > 0.9 is recommended, but > 0.8 is acceptable. ENCODE\ \ processed alignments file {ENCFF278LWC|/files/ENCFF278LWC/} processed by ChIP-seq\ \ ENCODE3 GRCh38 pipeline was generated from a library with PBC1 value of 0.80.\n\ \n**audit\\_warning**: PBC2 (PCR Bottlenecking Coefficient 2, M1/M2) is the ratio\ \ of the number of genomic locations where exactly one read maps uniquely (M1)\ \ to the number of genomic locations where two reads map uniquely (M2). A PBC2\ \ value in the range 0 - 1 is severe bottlenecking, 1 - 3 is moderate bottlenecking,\ \ 3 - 10 is mild bottlenecking, > 10 is no bottlenecking. PBC2 value > 10 is recommended,\ \ but > 3 is acceptable. ENCODE processed alignments file {ENCFF278LWC|/files/ENCFF278LWC/}\ \ processed by ChIP-seq ENCODE3 GRCh38 pipeline was generated from a library with\ \ PBC2 value of 5.39.\n\n**audit\\_warning**: PBC1 (PCR Bottlenecking Coefficient\ \ 1, M1/M\\_distinct) is the ratio of the number of genomic locations where exactly\ \ one read maps uniquely (M1) to the number of genomic locations where some reads\ \ map (M\\_distinct). A PBC1 value in the range 0 - 0.5 is severe bottlenecking,\ \ 0.5 - 0.8 is moderate bottlenecking, 0.8 - 0.9 is mild bottlenecking, and >\ \ 0.9 is no bottlenecking. PBC1 value > 0.9 is recommended, but > 0.8 is acceptable.\ \ ENCODE processed alignments file {ENCFF692VVV|/files/ENCFF692VVV/} processed\ \ by ChIP-seq ENCODE3 GRCh38 pipeline was generated from a library with PBC1 value\ \ of 0.87.\n\n**audit\\_warning**: PBC2 (PCR Bottlenecking Coefficient 2, M1/M2)\ \ is the ratio of the number of genomic locations where exactly one read maps\ \ uniquely (M1) to the number of genomic locations where two reads map uniquely\ \ (M2). A PBC2 value in the range 0 - 1 is severe bottlenecking, 1 - 3 is moderate\ \ bottlenecking, 3 - 10 is mild bottlenecking, > 10 is no bottlenecking. PBC2\ \ value > 10 is recommended, but > 3 is acceptable. ENCODE processed alignments\ \ file {ENCFF692VVV|/files/ENCFF692VVV/} processed by ChIP-seq ENCODE3 GRCh38\ \ pipeline was generated from a library with PBC2 value of 8.54." labels: reference_genome: hg38/genomes/GRCh38-hg38 accession: ENCSR000DPS status: released assay_term_name: ChIP-seq simple_biosample_summary: '' biosample_summary: Homo sapiens AG09319 replication_type: isogenic biosample_ontology: /biosample-types/cell_line_CLO_0021754/ perturbed: false doi: 10.17989/ENCSR000DPS date_created: '2014-01-14T22:00:28.348953+00:00' date_released: '2011-03-17' submitter_comment: Replicate 1,1 of this experiment was previously attributed to biosample ENCBS443ENC and replicate 2,1 of this experiment was previously attributed to biosample ENCBS443ENC but they have since been corrected to the current biosamples. Please note that the biosample term has remain unchanged. target: CTCF