type: position_score
table:
  filename: ENCFF046FWB.tabix.bed.gz
  header_mode: none
  zero_based: true
  format: tabix
  chrom:
    column_index: 0
  pos_begin:
    column_index: 1
  pos_end:
    column_index: 2
scores:
- id: Histone_ChIP-seq_ENCSR771QCM
  column_index: 3
  type: float
  desc: signal
  histogram:
    type: number
    number_of_bins: 100
meta:
  summary: 'ChIP-seq ENCSR771QCM [TISSUE: Homo sapiens SU-DHL-6, TARGET: H3F3A]'
  description: "**status**: released\n\n**biological\\_replicates**: Rep 1, Rep 2\n\
    \n**summary**: \n\n**output\\_type**: replicated peaks\n\n**audit\\_internal\\\
    _action**: Archived analysis {ENCAN669QQW|/analyses/ENCAN669QQW/} has in progress\
    \ subobject quality standard {encode3-histone-chip|/quality-standards/encode3-histone-chip/}\n\
    \n**audit\\_not\\_compliant**: Processed alignments file {ENCFF033JLT|/files/ENCFF033JLT/}\
    \ processed by ChIP-seq ENCODE3 GRCh38 pipeline has 23560132 usable fragments.\
    \ The minimum ENCODE standard for each replicate in a ChIP-seq experiment targeting\
    \ H3F3A-human and investigated as a broad histone mark is 20 million usable fragments.\
    \ The recommended value is > 45 million, but > 35 million is acceptable. (See\
    \ {ENCODE ChIP-seq data standards|/data-standards/chip-seq/})\n\n**audit\\_not\\\
    _compliant**: Processed alignments file {ENCFF559HLS|/files/ENCFF559HLS/} processed\
    \ by ChIP-seq ENCODE3 GRCh38 pipeline has 20740621 usable fragments. The minimum\
    \ ENCODE standard for each replicate in a ChIP-seq experiment targeting H3F3A-human\
    \ and investigated as a broad histone mark is 20 million usable fragments. The\
    \ recommended value is > 45 million, but > 35 million is acceptable. (See {ENCODE\
    \ ChIP-seq data standards|/data-standards/chip-seq/})\n\n**audit\\_warning**:\
    \ PBC1 (PCR Bottlenecking Coefficient 1, M1/M\\_distinct) is the ratio of the\
    \ number of genomic locations where exactly one read maps uniquely (M1) to the\
    \ number of genomic locations where some reads map (M\\_distinct). A PBC1 value\
    \ in the range 0 - 0.5 is severe bottlenecking, 0.5 - 0.8 is moderate bottlenecking,\
    \ 0.8 - 0.9 is mild bottlenecking, and > 0.9 is no bottlenecking. PBC1 value >\
    \ 0.9 is recommended, but > 0.8 is acceptable. ENCODE processed alignments file\
    \ {ENCFF033JLT|/files/ENCFF033JLT/} processed by ChIP-seq ENCODE3 GRCh38 pipeline\
    \ was generated from a library with PBC1 value of 0.87.\n\n**audit\\_warning**:\
    \ PBC2 (PCR Bottlenecking Coefficient 2, M1/M2) is the ratio of the number of\
    \ genomic locations where exactly one read maps uniquely (M1) to the number of\
    \ genomic locations where two reads map uniquely (M2). A PBC2 value in the range\
    \ 0 - 1 is severe bottlenecking, 1 - 3 is moderate bottlenecking, 3 - 10 is mild\
    \ bottlenecking, > 10 is no bottlenecking. PBC2 value > 10 is recommended, but\
    \ > 3 is acceptable. ENCODE processed alignments file {ENCFF033JLT|/files/ENCFF033JLT/}\
    \ processed by ChIP-seq ENCODE3 GRCh38 pipeline was generated from a library with\
    \ PBC2 value of 7.79."
  labels:
    reference_genome: hg38/genomes/GRCh38-hg38
    accession: ENCSR771QCM
    status: released
    assay_term_name: ChIP-seq
    simple_biosample_summary: ''
    biosample_summary: Homo sapiens SU-DHL-6
    replication_type: isogenic
    biosample_ontology: /biosample-types/cell_line_EFO_0002357/
    perturbed: false
    doi: 10.17989/ENCSR771QCM
    date_created: '2015-05-19T15:24:21.500165+00:00'
    date_released: '2016-12-05'
    submitter_comment: As of March 23rd, 2017, mappings and peaks have been rerun
      to 36bps to match with its control.
    target: H3F3A