type: position_score table: filename: ENCFF043LUG.tabix.bed.gz header_mode: none zero_based: true format: tabix chrom: column_index: 0 pos_begin: column_index: 1 pos_end: column_index: 2 scores: - id: Histone_ChIP-seq_ENCSR657RRI column_index: 3 type: float desc: signal histogram: type: number number_of_bins: 100 meta: summary: 'ChIP-seq ENCSR657RRI [TISSUE: Homo sapiens Loucy, TARGET: H3K4me3]' description: "**status**: released\n\n**biological\\_replicates**: Rep 1, Rep 2\n\ \n**summary**: \n\n**output\\_type**: replicated peaks\n\n**audit\\_internal\\\ _action**: Archived analysis {ENCAN091FCZ|/analyses/ENCAN091FCZ/} has in progress\ \ subobject quality standard {encode3-histone-chip|/quality-standards/encode3-histone-chip/}\n\ \n**audit\\_not\\_compliant**: NRF (Non Redundant Fraction) is equal to the result\ \ of the division of the number of reads after duplicates removal by the total\ \ number of reads. An NRF value in the range 0 - 0.5 is poor complexity, 0.5 -\ \ 0.8 is moderate complexity, and > 0.8 high complexity. NRF value > 0.8 is recommended,\ \ but > 0.5 is acceptable. ENCODE processed alignments file {ENCFF955GED|/files/ENCFF955GED/}\ \ processed by ChIP-seq ENCODE3 hg19 pipeline was generated from a library with\ \ NRF value of 0.47.\n\n**audit\\_warning**: PBC1 (PCR Bottlenecking Coefficient\ \ 1, M1/M\\_distinct) is the ratio of the number of genomic locations where exactly\ \ one read maps uniquely (M1) to the number of genomic locations where some reads\ \ map (M\\_distinct). A PBC1 value in the range 0 - 0.5 is severe bottlenecking,\ \ 0.5 - 0.8 is moderate bottlenecking, 0.8 - 0.9 is mild bottlenecking, and >\ \ 0.9 is no bottlenecking. PBC1 value > 0.9 is recommended, but > 0.8 is acceptable.\ \ ENCODE processed alignments file {ENCFF955GED|/files/ENCFF955GED/} processed\ \ by ChIP-seq ENCODE3 hg19 pipeline was generated from a library with PBC1 value\ \ of 0.50.\n\n**audit\\_warning**: PBC2 (PCR Bottlenecking Coefficient 2, M1/M2)\ \ is the ratio of the number of genomic locations where exactly one read maps\ \ uniquely (M1) to the number of genomic locations where two reads map uniquely\ \ (M2). A PBC2 value in the range 0 - 1 is severe bottlenecking, 1 - 3 is moderate\ \ bottlenecking, 3 - 10 is mild bottlenecking, > 10 is no bottlenecking. PBC2\ \ value > 10 is recommended, but > 3 is acceptable. ENCODE processed alignments\ \ file {ENCFF955GED|/files/ENCFF955GED/} processed by ChIP-seq ENCODE3 hg19 pipeline\ \ was generated from a library with PBC2 value of 2.27.\n\n**audit\\_warning**:\ \ PBC1 (PCR Bottlenecking Coefficient 1, M1/M\\_distinct) is the ratio of the\ \ number of genomic locations where exactly one read maps uniquely (M1) to the\ \ number of genomic locations where some reads map (M\\_distinct). A PBC1 value\ \ in the range 0 - 0.5 is severe bottlenecking, 0.5 - 0.8 is moderate bottlenecking,\ \ 0.8 - 0.9 is mild bottlenecking, and > 0.9 is no bottlenecking. PBC1 value >\ \ 0.9 is recommended, but > 0.8 is acceptable. ENCODE processed alignments file\ \ {ENCFF912DEA|/files/ENCFF912DEA/} processed by ChIP-seq ENCODE3 hg19 pipeline\ \ was generated from a library with PBC1 value of 0.83.\n\n**audit\\_warning**:\ \ PBC2 (PCR Bottlenecking Coefficient 2, M1/M2) is the ratio of the number of\ \ genomic locations where exactly one read maps uniquely (M1) to the number of\ \ genomic locations where two reads map uniquely (M2). A PBC2 value in the range\ \ 0 - 1 is severe bottlenecking, 1 - 3 is moderate bottlenecking, 3 - 10 is mild\ \ bottlenecking, > 10 is no bottlenecking. PBC2 value > 10 is recommended, but\ \ > 3 is acceptable. ENCODE processed alignments file {ENCFF912DEA|/files/ENCFF912DEA/}\ \ processed by ChIP-seq ENCODE3 hg19 pipeline was generated from a library with\ \ PBC2 value of 6.06." labels: reference_genome: hg38/genomes/GRCh38-hg38 accession: ENCSR657RRI status: released assay_term_name: ChIP-seq simple_biosample_summary: '' biosample_summary: Homo sapiens Loucy replication_type: isogenic biosample_ontology: /biosample-types/cell_line_EFO_0007112/ perturbed: false doi: 10.17989/ENCSR657RRI date_created: '2014-02-20T05:42:12.131519+00:00' date_released: '2014-09-04' submitter_comment: '' target: H3K4me3