type: position_score
table:
  filename: ENCFF718YSW.tabix.bed.gz
  header_mode: none
  zero_based: true
  format: tabix
  chrom:
    column_index: 0
  pos_begin:
    column_index: 1
  pos_end:
    column_index: 2
scores:
- id: Histone_ChIP-seq_ENCSR536SZD
  column_index: 3
  type: float
  desc: signal
  histogram:
    type: number
    number_of_bins: 100
meta:
  summary: 'ChIP-seq ENCSR536SZD [TISSUE: Homo sapiens NCI-H929, TARGET: H3F3A]'
  description: "**status**: released\n\n**biological\\_replicates**: Rep 1, Rep 2\n\
    \n**summary**: \n\n**output\\_type**: pseudoreplicated peaks\n\n**audit\\_internal\\\
    _action**: Released analysis {ENCAN700AAK|/analyses/ENCAN700AAK/} has in progress\
    \ subobject quality standard {encode4-histone-chip|/quality-standards/encode4-histone-chip/}\n\
    \n**audit\\_not\\_compliant**: Processed alignments file {ENCFF678EEL|/files/ENCFF678EEL/}\
    \ processed by ChIP-seq ENCODE4 v1.6.1 GRCh38 pipeline has 27903305 usable fragments.\
    \ The minimum ENCODE standard for each replicate in a ChIP-seq experiment targeting\
    \ H3F3A-human and investigated as a broad histone mark is 20 million usable fragments.\
    \ The recommended value is > 45 million, but > 35 million is acceptable. (See\
    \ {ENCODE ChIP-seq data standards|/data-standards/chip-seq/})\n\n**audit\\_warning**:\
    \ Processed alignments file {ENCFF806GPM|/files/ENCFF806GPM/} processed by ChIP-seq\
    \ ENCODE4 v1.6.1 GRCh38 pipeline has 35871436 usable fragments. The minimum ENCODE\
    \ standard for each replicate in a ChIP-seq experiment targeting H3F3A-human and\
    \ investigated as a broad histone mark is 20 million usable fragments. The recommended\
    \ value is > 45 million, but > 35 million is acceptable. (See {ENCODE ChIP-seq\
    \ data standards|/data-standards/chip-seq/})\n\n**audit\\_warning**: PBC1 (PCR\
    \ Bottlenecking Coefficient 1, M1/M\\_distinct) is the ratio of the number of\
    \ genomic locations where exactly one read maps uniquely (M1) to the number of\
    \ genomic locations where some reads map (M\\_distinct). A PBC1 value in the range\
    \ 0 - 0.5 is severe bottlenecking, 0.5 - 0.8 is moderate bottlenecking, 0.8 -\
    \ 0.9 is mild bottlenecking, and > 0.9 is no bottlenecking. PBC1 value > 0.9 is\
    \ recommended, but > 0.8 is acceptable. ENCODE processed alignments file {ENCFF806GPM|/files/ENCFF806GPM/}\
    \ processed by ChIP-seq ENCODE4 v1.6.1 GRCh38 pipeline was generated from a library\
    \ with PBC1 value of 0.88.\n\n**audit\\_warning**: PBC2 (PCR Bottlenecking Coefficient\
    \ 2, M1/M2) is the ratio of the number of genomic locations where exactly one\
    \ read maps uniquely (M1) to the number of genomic locations where two reads map\
    \ uniquely (M2). A PBC2 value in the range 0 - 1 is severe bottlenecking, 1 -\
    \ 3 is moderate bottlenecking, 3 - 10 is mild bottlenecking, > 10 is no bottlenecking.\
    \ PBC2 value > 10 is recommended, but > 3 is acceptable. ENCODE processed alignments\
    \ file {ENCFF806GPM|/files/ENCFF806GPM/} processed by ChIP-seq ENCODE4 v1.6.1\
    \ GRCh38 pipeline was generated from a library with PBC2 value of 7.93."
  labels:
    reference_genome: hg38/genomes/GRCh38-hg38
    accession: ENCSR536SZD
    status: released
    assay_term_name: ChIP-seq
    simple_biosample_summary: ''
    biosample_summary: Homo sapiens NCI-H929
    replication_type: isogenic
    biosample_ontology: /biosample-types/cell_line_EFO_0001221/
    perturbed: false
    doi: 10.17989/ENCSR536SZD
    date_created: '2015-05-23T03:46:39.735766+00:00'
    date_released: '2017-01-13'
    submitter_comment: ''
    target: H3F3A