type: position_score
table:
  filename: ENCFF491CKX.tabix.bed.gz
  header_mode: none
  zero_based: true
  format: tabix
  chrom:
    column_index: 0
  pos_begin:
    column_index: 1
  pos_end:
    column_index: 2
scores:
- id: Histone_ChIP-seq_ENCSR453GNY
  column_index: 3
  type: float
  desc: signal
  histogram:
    type: number
    number_of_bins: 100
meta:
  summary: 'ChIP-seq ENCSR453GNY [TISSUE: Homo sapiens CD4-positive, alpha-beta T
    cell, TARGET: H3K9me3]'
  description: "**status**: released\n\n**biological\\_replicates**: Rep 1, Rep 2\n\
    \n**summary**: \n\n**output\\_type**: replicated peaks\n\n**audit\\_internal\\\
    _action**: Archived analysis {ENCAN809ZWL|/analyses/ENCAN809ZWL/} has in progress\
    \ subobject quality standard {encode3-histone-chip|/quality-standards/encode3-histone-chip/}\n\
    \n**audit\\_not\\_compliant**: Processed unfiltered alignments file {ENCFF810ZXM|/files/ENCFF810ZXM/}\
    \ processed by ChIP-seq ENCODE3 hg19 pipeline has 34769293 mapped reads. The minimum\
    \ ENCODE standard for each replicate in a ChIP-seq experiment targeting H3K9me3-human\
    \ and investigated as a broad histone mark is 35 million mapped reads. The recommended\
    \ value is > 45 million, but > 35 million is acceptable. (See {ENCODE ChIP-seq\
    \ data standards|/data-standards/chip-seq/})\n\n**audit\\_not\\_compliant**: Processed\
    \ redacted unfiltered alignments file {ENCFF971ENT|/files/ENCFF971ENT/} processed\
    \ by ChIP-seq ENCODE3 hg19 pipeline has 26966218 mapped reads. The minimum ENCODE\
    \ standard for each replicate in a ChIP-seq experiment targeting H3K9me3-human\
    \ and investigated as a broad histone mark is 35 million mapped reads. The recommended\
    \ value is > 45 million, but > 35 million is acceptable. (See {ENCODE ChIP-seq\
    \ data standards|/data-standards/chip-seq/})\n\n**audit\\_warning**: PBC1 (PCR\
    \ Bottlenecking Coefficient 1, M1/M\\_distinct) is the ratio of the number of\
    \ genomic locations where exactly one read maps uniquely (M1) to the number of\
    \ genomic locations where some reads map (M\\_distinct). A PBC1 value in the range\
    \ 0 - 0.5 is severe bottlenecking, 0.5 - 0.8 is moderate bottlenecking, 0.8 -\
    \ 0.9 is mild bottlenecking, and > 0.9 is no bottlenecking. PBC1 value > 0.9 is\
    \ recommended, but > 0.8 is acceptable. ENCODE processed alignments file {ENCFF803BLL|/files/ENCFF803BLL/}\
    \ processed by ChIP-seq ENCODE3 hg19 pipeline was generated from a library with\
    \ PBC1 value of 0.82.\n\n**audit\\_warning**: PBC2 (PCR Bottlenecking Coefficient\
    \ 2, M1/M2) is the ratio of the number of genomic locations where exactly one\
    \ read maps uniquely (M1) to the number of genomic locations where two reads map\
    \ uniquely (M2). A PBC2 value in the range 0 - 1 is severe bottlenecking, 1 -\
    \ 3 is moderate bottlenecking, 3 - 10 is mild bottlenecking, > 10 is no bottlenecking.\
    \ PBC2 value > 10 is recommended, but > 3 is acceptable. ENCODE processed alignments\
    \ file {ENCFF803BLL|/files/ENCFF803BLL/} processed by ChIP-seq ENCODE3 hg19 pipeline\
    \ was generated from a library with PBC2 value of 5.50.\n\n**audit\\_warning**:\
    \ PBC1 (PCR Bottlenecking Coefficient 1, M1/M\\_distinct) is the ratio of the\
    \ number of genomic locations where exactly one read maps uniquely (M1) to the\
    \ number of genomic locations where some reads map (M\\_distinct). A PBC1 value\
    \ in the range 0 - 0.5 is severe bottlenecking, 0.5 - 0.8 is moderate bottlenecking,\
    \ 0.8 - 0.9 is mild bottlenecking, and > 0.9 is no bottlenecking. PBC1 value >\
    \ 0.9 is recommended, but > 0.8 is acceptable. ENCODE processed redacted alignments\
    \ file {ENCFF041XFT|/files/ENCFF041XFT/} processed by ChIP-seq ENCODE3 hg19 pipeline\
    \ was generated from a library with PBC1 value of 0.84.\n\n**audit\\_warning**:\
    \ PBC2 (PCR Bottlenecking Coefficient 2, M1/M2) is the ratio of the number of\
    \ genomic locations where exactly one read maps uniquely (M1) to the number of\
    \ genomic locations where two reads map uniquely (M2). A PBC2 value in the range\
    \ 0 - 1 is severe bottlenecking, 1 - 3 is moderate bottlenecking, 3 - 10 is mild\
    \ bottlenecking, > 10 is no bottlenecking. PBC2 value > 10 is recommended, but\
    \ > 3 is acceptable. ENCODE processed redacted alignments file {ENCFF041XFT|/files/ENCFF041XFT/}\
    \ processed by ChIP-seq ENCODE3 hg19 pipeline was generated from a library with\
    \ PBC2 value of 6.30."
  labels:
    reference_genome: hg38/genomes/GRCh38-hg38
    accession: ENCSR453GNY
    status: released
    assay_term_name: ChIP-seq
    simple_biosample_summary: ''
    biosample_summary: Homo sapiens CD4-positive, alpha-beta T cell
    replication_type: anisogenic
    biosample_ontology: /biosample-types/primary_cell_CL_0000624/
    perturbed: false
    doi: 10.17989/ENCSR453GNY
    date_created: '2015-09-15T19:48:35.597029+00:00'
    date_released: '2013-07-31'
    submitter_comment: The raw data from at least one replicate is not available to
      the ENCODE consortium.
    target: H3K9me3