type: position_score
table:
  filename: ENCFF841LEO.tabix.bed.gz
  header_mode: none
  zero_based: true
  format: tabix
  chrom:
    column_index: 0
  pos_begin:
    column_index: 1
  pos_end:
    column_index: 2
scores:
- id: DNase-seq_ENCSR855FOP
  column_index: 3
  type: float
  desc: signal
  histogram:
    type: number
    number_of_bins: 100
meta:
  summary: 'DNase-seq ENCSR855FOP [TISSUE: Homo sapiens hematopoietic multipotent
    progenitor cell treated with interleukin-3 for 13 days, kit ligand for 13 days,
    hydrocortisone succinate for 13 days, erythropoietin for 13 days]'
  description: '**status**: released


    **biological\_replicates**: Rep 2


    **summary**: male adult (25 years) treated with interleukin-3 for 13 days, kit
    ligand for 13 days, hydrocortisone succinate for 13 days, erythropoietin for 13
    days


    **output\_type**: peaks


    **audit\_error**: Signal Portion of Tags (SPOT) is a measure of enrichment, analogous
    to the commonly used fraction of reads in peaks metric. ENCODE processed alignment
    files {ENCFF401MDW|/files/ENCFF401MDW/} processed by DNase-seq ENCODE3 GRCh38
    pipeline ({ENCPL001DNS|/pipelines/ENCPL001DNS/}) for GRCh38 assembly  have a SPOT1
    score of 0.23. According to ENCODE standards, SPOT1 score of 0.4 or higher is
    considered a product of high quality data. Any sample with a SPOT1 score <0.3
    should be targeted for replacement with a higher quality sample, and a SPOT1 score
    of 0.25 is considered minimally acceptable SPOT1 score of 0.25 is considered minimally
    acceptable for rare and hard to find primary tissues. (See {ENCODE DNase-seq data
    standards|/data-standards/dnase-seq/})


    **audit\_error**: Signal Portion of Tags (SPOT) is a measure of enrichment, analogous
    to the commonly used fraction of reads in peaks metric. ENCODE processed alignment
    files {ENCFF741PWD|/files/ENCFF741PWD/} processed by DNase-seq ENCODE3 GRCh38
    pipeline ({ENCPL001DNS|/pipelines/ENCPL001DNS/}) for GRCh38 assembly  have a SPOT1
    score of 0.18. According to ENCODE standards, SPOT1 score of 0.4 or higher is
    considered a product of high quality data. Any sample with a SPOT1 score <0.3
    should be targeted for replacement with a higher quality sample, and a SPOT1 score
    of 0.25 is considered minimally acceptable SPOT1 score of 0.25 is considered minimally
    acceptable for rare and hard to find primary tissues. (See {ENCODE DNase-seq data
    standards|/data-standards/dnase-seq/})


    **audit\_internal\_action**: Archived analysis {ENCAN851ACE|/analyses/ENCAN851ACE/}
    has in progress subobject quality standard {encode3-dnase|/quality-standards/encode3-dnase/}'
  labels:
    reference_genome: hg38/genomes/GRCh38-hg38
    accession: ENCSR855FOP
    status: released
    assay_term_name: DNase-seq
    simple_biosample_summary: male adult (25 years) treated with interleukin-3 for
      13 days, kit ligand for 13 days, hydrocortisone succinate for 13 days, erythropoietin
      for 13 days
    biosample_summary: Homo sapiens hematopoietic multipotent progenitor cell treated
      with interleukin-3 for 13 days, kit ligand for 13 days, hydrocortisone succinate
      for 13 days, erythropoietin for 13 days
    replication_type: isogenic
    biosample_ontology: /biosample-types/in_vitro_differentiated_cells_CL_0000837/
    perturbed: false
    doi: 10.17989/ENCSR855FOP
    date_created: '2015-03-29T22:10:49.668284+00:00'
    date_released: '2015-11-05'
    submitter_comment: ''