type: position_score
table:
  filename: ENCFF991ONF.tabix.bed.gz
  header_mode: none
  zero_based: true
  format: tabix
  chrom:
    column_index: 0
  pos_begin:
    column_index: 1
  pos_end:
    column_index: 2
scores:
- id: DNase-seq_ENCSR801VSK
  column_index: 3
  type: float
  desc: 'DNase-seq ENCSR801VSK [biosample_summary="Homo sapiens activated CD4-positive, alpha-beta T cell female adult (37 years) treated with 100 ng/mL Interleukin-4 for 8 hours, 50 U/mL Interleukin-2 for 16 hours, anti-CD3 and anti-CD28 coated beads for 16 hours"]'
  histogram:
    type: number
    number_of_bins: 100
meta:
  summary: 'DNase-seq ENCSR801VSK [biosample_summary="Homo sapiens activated CD4-positive, alpha-beta T cell female adult (37 years) treated with 100 ng/mL Interleukin-4 for 8 hours, 50 U/mL Interleukin-2 for 16 hours, anti-CD3 and anti-CD28 coated beads for 16 hours"]'
  description: '**status**: released


    **biological\_replicates**: Rep 1


    **summary**: female adult (37 years) treated with 100 ng/mL Interleukin-4 for
    8 hours, 50 U/mL Interleukin-2 for 16 hours, anti-CD3 and anti-CD28 coated beads
    for 16 hours


    **output\_type**: peaks


    **audit\_warning**: Signal Portion of Tags (SPOT) is a measure of enrichment,
    analogous to the commonly used fraction of reads in peaks metric. ENCODE processed
    alignment files {ENCFF220ACX|/files/ENCFF220ACX/} processed by DNase-seq ENCODE4
    v3.0.0-alpha.2 GRCh38 pipeline ({ENCPL848KLD|/pipelines/ENCPL848KLD/}) for GRCh38
    assembly  have a SPOT1 score of 0.37. According to ENCODE standards, SPOT1 score
    of 0.4 or higher is considered a product of high quality data. Any sample with
    a SPOT1 score <0.3 should be targeted for replacement with a higher quality sample,
    and a SPOT1 score of 0.25 is considered minimally acceptable SPOT1 score of 0.25
    is considered minimally acceptable for rare and hard to find primary tissues.
    (See {ENCODE DNase-seq data standards|/data-standards/dnase-seq-encode4/})'
  labels:
    reference_genome: hg38/genomes/GRCh38-hg38
    accession: ENCSR801VSK
    status: released
    assay_term_name: DNase-seq
    simple_biosample_summary: female adult (37 years) treated with 100 ng/mL Interleukin-4
      for 8 hours, 50 U/mL Interleukin-2 for 16 hours, anti-CD3 and anti-CD28 coated
      beads for 16 hours
    biosample_summary: Homo sapiens activated CD4-positive, alpha-beta T cell female
      adult (37 years) treated with 100 ng/mL Interleukin-4 for 8 hours, 50 U/mL Interleukin-2
      for 16 hours, anti-CD3 and anti-CD28 coated beads for 16 hours
    replication_type: unreplicated
    biosample_ontology: /biosample-types/primary_cell_CL_0000896/
    perturbed: false
    doi: 10.17989/ENCSR801VSK
    date_created: '2018-11-30T18:43:54.889291+00:00'
    date_released: '2020-09-23'
    submitter_comment: The experiment biosample had only one associated treatment
      Interleukin-4 (UniProtKB:P05112) for 8 hours. Treatments anti-CD3 and anti-CD28
      coated beads for 16 hours & 50 U/mL Interleukin-2 (UniProtKB:P60568) for 16
      hours have been added to the biosample on 11/04/21.