type: position_score table: filename: ENCFF010XTH.tabix.bed.gz header_mode: none zero_based: true format: tabix chrom: column_index: 0 pos_begin: column_index: 1 pos_end: column_index: 2 scores: - id: DNase-seq_ENCSR612IKQ column_index: 3 type: float desc: 'DNase-seq ENCSR612IKQ [biosample_summary="Homo sapiens with Cognitive impairment, Alzheimer''''s disease; posterior cingulate gyrus tissue female adult (87 years)"]' histogram: type: number number_of_bins: 100 meta: summary: 'DNase-seq ENCSR612IKQ [biosample_summary="Homo sapiens with Cognitive impairment, Alzheimer''''s disease; posterior cingulate gyrus tissue female adult (87 years)"]' description: '**status**: released **biological\_replicates**: Rep 1 **summary**: female adult (87 years) with Cognitive impairment, Alzheimer''s disease **output\_type**: peaks **audit\_warning**: Signal Portion of Tags (SPOT) is a measure of enrichment, analogous to the commonly used fraction of reads in peaks metric. ENCODE processed alignment files {ENCFF176HYT|/files/ENCFF176HYT/} processed by DNase-seq ENCODE4 v3.0.0-alpha.2 GRCh38 pipeline ({ENCPL848KLD|/pipelines/ENCPL848KLD/}) for GRCh38 assembly have a SPOT1 score of 0.28. According to ENCODE standards, SPOT1 score of 0.4 or higher is considered a product of high quality data. Any sample with a SPOT1 score <0.3 should be targeted for replacement with a higher quality sample, and a SPOT1 score of 0.25 is considered minimally acceptable SPOT1 score of 0.25 is considered minimally acceptable for rare and hard to find primary tissues. (See {ENCODE DNase-seq data standards|/data-standards/dnase-seq-encode4/})' labels: reference_genome: hg38/genomes/GRCh38-hg38 accession: ENCSR612IKQ status: released assay_term_name: DNase-seq simple_biosample_summary: female adult (87 years) with Cognitive impairment, Alzheimer's disease biosample_summary: Homo sapiens with Cognitive impairment, Alzheimer's disease; posterior cingulate gyrus tissue female adult (87 years) replication_type: unreplicated biosample_ontology: /biosample-types/tissue_UBERON_0002740/ perturbed: false doi: 10.17989/ENCSR612IKQ date_created: '2020-05-28T00:56:22.502954+00:00' date_released: '2020-09-28' submitter_comment: ''