type: position_score table: filename: ENCFF966AQE.tabix.bed.gz header_mode: none zero_based: true format: tabix chrom: column_index: 0 pos_begin: column_index: 1 pos_end: column_index: 2 scores: - id: DNase-seq_ENCSR330JXM column_index: 3 type: float desc: signal histogram: type: number number_of_bins: 100 meta: summary: 'DNase-seq ENCSR330JXM [TISSUE: Homo sapiens brain organoid, 90 days post differentiation]' description: '**status**: released **biological\_replicates**: Rep 1 **summary**: brain organoid 90 days post differentiation **output\_type**: peaks **audit\_error**: Signal Portion of Tags (SPOT) is a measure of enrichment, analogous to the commonly used fraction of reads in peaks metric. ENCODE processed alignment files {ENCFF424NSY|/files/ENCFF424NSY/} processed by DNase-seq ENCODE4 v3.0.0 GRCh38 pipeline ({ENCPL848KLD|/pipelines/ENCPL848KLD/}) for GRCh38 assembly have a SPOT1 score of 0.22. According to ENCODE standards, SPOT1 score of 0.4 or higher is considered a product of high quality data. Any sample with a SPOT1 score <0.3 should be targeted for replacement with a higher quality sample, and a SPOT1 score of 0.25 is considered minimally acceptable SPOT1 score of 0.25 is considered minimally acceptable for rare and hard to find primary tissues. (See {ENCODE DNase-seq data standards|/data-standards/dnase-seq-encode4/})' labels: reference_genome: hg38/genomes/GRCh38-hg38 accession: ENCSR330JXM status: released assay_term_name: DNase-seq simple_biosample_summary: brain organoid 90 days post differentiation biosample_summary: Homo sapiens brain organoid, 90 days post differentiation replication_type: unreplicated biosample_ontology: /biosample-types/organoid_UBERON_0000955/ perturbed: false doi: 10.17989/ENCSR330JXM date_created: '2021-09-02T20:46:52.365092+00:00' date_released: '2021-09-10' submitter_comment: ''