type: position_score table: filename: ENCFF601IBY.tabix.bed.gz header_mode: none zero_based: true format: tabix chrom: column_index: 0 pos_begin: column_index: 1 pos_end: column_index: 2 scores: - id: DNase-seq_ENCSR274FZD column_index: 3 type: float desc: 'DNase-seq ENCSR274FZD [biosample_summary="Homo sapiens with Cognitive impairment, Alzheimer''''s disease; head of caudate nucleus tissue female adult (90 or above years)"]' histogram: type: number number_of_bins: 100 meta: summary: 'DNase-seq ENCSR274FZD [biosample_summary="Homo sapiens with Cognitive impairment, Alzheimer''''s disease; head of caudate nucleus tissue female adult (90 or above years)"]' description: '**status**: released **biological\_replicates**: Rep 1 **summary**: female adult (90 or above years) with Cognitive impairment, Alzheimer''s disease **output\_type**: peaks **audit\_warning**: Signal Portion of Tags (SPOT) is a measure of enrichment, analogous to the commonly used fraction of reads in peaks metric. ENCODE processed alignment files {ENCFF773CBJ|/files/ENCFF773CBJ/} processed by DNase-seq ENCODE4 v3.0.0 GRCh38 pipeline ({ENCPL848KLD|/pipelines/ENCPL848KLD/}) for GRCh38 assembly have a SPOT1 score of 0.34. According to ENCODE standards, SPOT1 score of 0.4 or higher is considered a product of high quality data. Any sample with a SPOT1 score <0.3 should be targeted for replacement with a higher quality sample, and a SPOT1 score of 0.25 is considered minimally acceptable SPOT1 score of 0.25 is considered minimally acceptable for rare and hard to find primary tissues. (See {ENCODE DNase-seq data standards|/data-standards/dnase-seq-encode4/})' labels: reference_genome: hg38/genomes/GRCh38-hg38 accession: ENCSR274FZD status: released assay_term_name: DNase-seq simple_biosample_summary: female adult (90 or above years) with Cognitive impairment, Alzheimer's disease biosample_summary: Homo sapiens with Cognitive impairment, Alzheimer's disease; head of caudate nucleus tissue female adult (90 or above years) replication_type: unreplicated biosample_ontology: /biosample-types/tissue_UBERON_0002626/ perturbed: false doi: 10.17989/ENCSR274FZD date_created: '2021-04-01T15:48:57.751634+00:00' date_released: '2021-06-17' submitter_comment: ''