type: position_score
table:
  filename: ENCFF011PUO.tabix.bed.gz
  header_mode: none
  zero_based: true
  format: tabix
  chrom:
    column_index: 0
  pos_begin:
    column_index: 1
  pos_end:
    column_index: 2
scores:
- id: DNase-seq_ENCSR266NDC
  column_index: 3
  type: float
  desc: signal
  histogram:
    type: number
    number_of_bins: 100
meta:
  summary: 'DNase-seq ENCSR266NDC [TISSUE: Homo sapiens stimulated activated CD4-positive,
    alpha-beta T cell female adult (33 years) treated with anti-CD3 and anti-CD28
    coated beads for 1 hour, 100 ng/mL TNF-alpha for 1 hour]'
  description: '**status**: released


    **biological\_replicates**: Rep 1


    **summary**: female adult (33 years) treated with anti-CD3 and anti-CD28 coated
    beads for 1 hour, 100 ng/mL TNF-alpha for 1 hour


    **output\_type**: peaks


    **audit\_warning**: Alignment file {ENCFF503HKL|/files/ENCFF503HKL/} processed
    by DNase-seq ENCODE4 v3.0.0-alpha.2 GRCh38 pipeline ( {ENCPL848KLD|/pipelines/ENCPL848KLD/}
    ) for GRCh38 assembly has 31164880 mapped reads. According to ENCODE standards,
    conventional DNase-seq profile requires a minimum of 20 million uniquely mapped
    reads to generate a reliable SPOT (Signal Portion of Tags) score. The recommended
    value is > 50 million. For deep, foot-printing depth DNase-seq 150-200 million
    uniquely mapped reads are recommended. (See {ENCODE DNase-seq data standards|/data-standards/dnase-seq-encode4/})'
  labels:
    reference_genome: hg38/genomes/GRCh38-hg38
    accession: ENCSR266NDC
    status: released
    assay_term_name: DNase-seq
    simple_biosample_summary: female adult (33 years) treated with anti-CD3 and anti-CD28
      coated beads for 1 hour, 100 ng/mL TNF-alpha for 1 hour
    biosample_summary: Homo sapiens stimulated activated CD4-positive, alpha-beta
      T cell female adult (33 years) treated with anti-CD3 and anti-CD28 coated beads
      for 1 hour, 100 ng/mL TNF-alpha for 1 hour
    replication_type: unreplicated
    biosample_ontology: /biosample-types/primary_cell_NTR_0000663/
    perturbed: false
    doi: 10.17989/ENCSR266NDC
    date_created: '2020-04-18T22:21:50.988777+00:00'
    date_released: '2020-09-23'
    submitter_comment: ''