type: position_score table: filename: ENCFF044QJS.tabix.bed.gz header_mode: none zero_based: true format: tabix chrom: column_index: 0 pos_begin: column_index: 1 pos_end: column_index: 2 scores: - id: DNase-seq_ENCSR217SET column_index: 3 type: float desc: signal histogram: type: number number_of_bins: 100 meta: summary: 'DNase-seq ENCSR217SET [TISSUE: Homo sapiens SW480]' description: "**status**: released\n\n**biological\\_replicates**: Rep 2\n\n**summary**:\ \ \n\n**output\\_type**: peaks\n\n**audit\\_internal\\_action**: Archived analysis\ \ {ENCAN714NWB|/analyses/ENCAN714NWB/} has in progress subobject quality standard\ \ {encode3-dnase|/quality-standards/encode3-dnase/}\n\n**audit\\_warning**: Signal\ \ Portion of Tags (SPOT) is a measure of enrichment, analogous to the commonly\ \ used fraction of reads in peaks metric. ENCODE processed alignment files {ENCFF080TUY|/files/ENCFF080TUY/}\ \ processed by DNase-seq ENCODE3 GRCh38 pipeline ({ENCPL202DNS|/pipelines/ENCPL202DNS/})\ \ for GRCh38 assembly have a SPOT1 score of 0.39. According to ENCODE standards,\ \ SPOT1 score of 0.4 or higher is considered a product of high quality data. Any\ \ sample with a SPOT1 score <0.3 should be targeted for replacement with a higher\ \ quality sample, and a SPOT1 score of 0.25 is considered minimally acceptable\ \ SPOT1 score of 0.25 is considered minimally acceptable for rare and hard to\ \ find primary tissues. (See {ENCODE DNase-seq data standards|/data-standards/dnase-seq/})\n\ \n**audit\\_warning**: Signal Portion of Tags (SPOT) is a measure of enrichment,\ \ analogous to the commonly used fraction of reads in peaks metric. ENCODE processed\ \ alignment files {ENCFF242UZF|/files/ENCFF242UZF/} processed by DNase-seq ENCODE3\ \ GRCh38 pipeline ({ENCPL202DNS|/pipelines/ENCPL202DNS/}) for GRCh38 assembly\ \ have a SPOT1 score of 0.32. According to ENCODE standards, SPOT1 score of 0.4\ \ or higher is considered a product of high quality data. Any sample with a SPOT1\ \ score <0.3 should be targeted for replacement with a higher quality sample,\ \ and a SPOT1 score of 0.25 is considered minimally acceptable SPOT1 score of\ \ 0.25 is considered minimally acceptable for rare and hard to find primary tissues.\ \ (See {ENCODE DNase-seq data standards|/data-standards/dnase-seq/})" labels: reference_genome: hg38/genomes/GRCh38-hg38 accession: ENCSR217SET status: released assay_term_name: DNase-seq simple_biosample_summary: '' biosample_summary: Homo sapiens SW480 replication_type: isogenic biosample_ontology: /biosample-types/cell_line_EFO_0002083/ perturbed: false doi: 10.17989/ENCSR217SET date_created: '2015-12-15T08:27:36.760630+00:00' date_released: '2016-05-09' submitter_comment: ''