type: position_score
table:
  filename: ENCFF515CNP.tabix.bed.gz
  header_mode: none
  zero_based: true
  format: tabix
  chrom:
    column_index: 0
  pos_begin:
    column_index: 1
  pos_end:
    column_index: 2
scores:
- id: DNase-seq_ENCSR115YPI
  column_index: 3
  type: float
  desc: signal
  histogram:
    type: number
    number_of_bins: 100
meta:
  summary: 'DNase-seq ENCSR115YPI [TISSUE: Homo sapiens hematopoietic multipotent
    progenitor cell treated with erythropoietin for 20 days, hydrocortisone succinate
    for 20 days, kit ligand for 20 days, interleukin-3 for 20 days]'
  description: '**status**: released


    **biological\_replicates**: Rep 1


    **summary**: male adult (25 years) treated with erythropoietin for 20 days, hydrocortisone
    succinate for 20 days, kit ligand for 20 days, interleukin-3 for 20 days


    **output\_type**: peaks


    **audit\_error**: Signal Portion of Tags (SPOT) is a measure of enrichment, analogous
    to the commonly used fraction of reads in peaks metric. ENCODE processed alignment
    files {ENCFF986NWU|/files/ENCFF986NWU/} processed by DNase-seq ENCODE3 GRCh38
    pipeline ({ENCPL202DNS|/pipelines/ENCPL202DNS/}) for GRCh38 assembly  have a SPOT1
    score of 0.22. According to ENCODE standards, SPOT1 score of 0.4 or higher is
    considered a product of high quality data. Any sample with a SPOT1 score <0.3
    should be targeted for replacement with a higher quality sample, and a SPOT1 score
    of 0.25 is considered minimally acceptable SPOT1 score of 0.25 is considered minimally
    acceptable for rare and hard to find primary tissues. (See {ENCODE DNase-seq data
    standards|/data-standards/dnase-seq/})


    **audit\_internal\_action**: Archived analysis {ENCAN637UOT|/analyses/ENCAN637UOT/}
    has in progress subobject quality standard {encode3-dnase|/quality-standards/encode3-dnase/}'
  labels:
    reference_genome: hg38/genomes/GRCh38-hg38
    accession: ENCSR115YPI
    status: released
    assay_term_name: DNase-seq
    simple_biosample_summary: male adult (25 years) treated with erythropoietin for
      20 days, hydrocortisone succinate for 20 days, kit ligand for 20 days, interleukin-3
      for 20 days
    biosample_summary: Homo sapiens hematopoietic multipotent progenitor cell treated
      with erythropoietin for 20 days, hydrocortisone succinate for 20 days, kit ligand
      for 20 days, interleukin-3 for 20 days
    replication_type: unreplicated
    biosample_ontology: /biosample-types/in_vitro_differentiated_cells_CL_0000837/
    perturbed: false
    doi: 10.17989/ENCSR115YPI
    date_created: '2018-02-23T17:25:08.532094+00:00'
    date_released: '2018-05-09'
    submitter_comment: ''