type: position_score table: filename: ENCFF935XVZ.tabix.bed.gz header_mode: none zero_based: true format: tabix chrom: column_index: 0 pos_begin: column_index: 1 pos_end: column_index: 2 scores: - id: DNase-seq_ENCSR062DUU column_index: 3 type: float desc: 'DNase-seq ENCSR062DUU [biosample_summary="Homo sapiens stomach tissue female embryo (105 days)"]' histogram: type: number number_of_bins: 100 meta: summary: 'DNase-seq ENCSR062DUU [biosample_summary="Homo sapiens stomach tissue female embryo (105 days)"]' description: '**status**: released **biological\_replicates**: Rep 1 **summary**: female embryo (105 days) **output\_type**: peaks **audit\_warning**: Replicate 1\_2 has no significant footprints detected. **audit\_warning**: Alignment file {ENCFF651VUW|/files/ENCFF651VUW/} processed by DNase-seq ENCODE4 v3.0.0-alpha.2 GRCh38 pipeline ( {ENCPL848KLD|/pipelines/ENCPL848KLD/} ) for GRCh38 assembly has 34450254 mapped reads. According to ENCODE standards, conventional DNase-seq profile requires a minimum of 20 million uniquely mapped reads to generate a reliable SPOT (Signal Portion of Tags) score. The recommended value is > 50 million. For deep, foot-printing depth DNase-seq 150-200 million uniquely mapped reads are recommended. (See {ENCODE DNase-seq data standards|/data-standards/dnase-seq-encode4/}) **audit\_warning**: Signal Portion of Tags (SPOT) is a measure of enrichment, analogous to the commonly used fraction of reads in peaks metric. ENCODE processed alignment files {ENCFF651VUW|/files/ENCFF651VUW/} processed by DNase-seq ENCODE4 v3.0.0-alpha.2 GRCh38 pipeline ({ENCPL848KLD|/pipelines/ENCPL848KLD/}) for GRCh38 assembly have a SPOT1 score of 0.29. According to ENCODE standards, SPOT1 score of 0.4 or higher is considered a product of high quality data. Any sample with a SPOT1 score <0.3 should be targeted for replacement with a higher quality sample, and a SPOT1 score of 0.25 is considered minimally acceptable SPOT1 score of 0.25 is considered minimally acceptable for rare and hard to find primary tissues. (See {ENCODE DNase-seq data standards|/data-standards/dnase-seq-encode4/})' labels: reference_genome: hg38/genomes/GRCh38-hg38 accession: ENCSR062DUU status: released assay_term_name: DNase-seq simple_biosample_summary: female embryo (105 days) biosample_summary: Homo sapiens stomach tissue female embryo (105 days) replication_type: unreplicated biosample_ontology: /biosample-types/tissue_UBERON_0000945/ perturbed: false doi: 10.17989/ENCSR062DUU date_created: '2015-09-16T21:42:23.998475+00:00' date_released: '2013-07-31' submitter_comment: ''