type: position_score
table:
  filename: ENCFF844CAH.tabix.bed.gz
  header_mode: none
  zero_based: true
  format: tabix
  chrom:
    column_index: 0
  pos_begin:
    column_index: 1
  pos_end:
    column_index: 2
scores:
- id: DNase-seq_ENCSR049SVH
  column_index: 3
  type: float
  desc: signal
  histogram:
    type: number
    number_of_bins: 100
meta:
  summary: 'DNase-seq ENCSR049SVH [TISSUE: Homo sapiens brain organoid, 180 days post
    differentiation]'
  description: '**status**: released


    **biological\_replicates**: Rep 1


    **summary**: brain organoid 180 days post differentiation


    **output\_type**: peaks


    **audit\_error**: Signal Portion of Tags (SPOT) is a measure of enrichment, analogous
    to the commonly used fraction of reads in peaks metric. ENCODE processed alignment
    files {ENCFF786YZF|/files/ENCFF786YZF/} processed by DNase-seq ENCODE4 v3.0.0
    GRCh38 pipeline ({ENCPL848KLD|/pipelines/ENCPL848KLD/}) for GRCh38 assembly  have
    a SPOT1 score of 0.24. According to ENCODE standards, SPOT1 score of 0.4 or higher
    is considered a product of high quality data. Any sample with a SPOT1 score <0.3
    should be targeted for replacement with a higher quality sample, and a SPOT1 score
    of 0.25 is considered minimally acceptable SPOT1 score of 0.25 is considered minimally
    acceptable for rare and hard to find primary tissues. (See {ENCODE DNase-seq data
    standards|/data-standards/dnase-seq-encode4/})'
  labels:
    reference_genome: hg38/genomes/GRCh38-hg38
    accession: ENCSR049SVH
    status: released
    assay_term_name: DNase-seq
    simple_biosample_summary: brain organoid 180 days post differentiation
    biosample_summary: Homo sapiens brain organoid, 180 days post differentiation
    replication_type: unreplicated
    biosample_ontology: /biosample-types/organoid_UBERON_0000955/
    perturbed: false
    doi: 10.17989/ENCSR049SVH
    date_created: '2021-08-31T22:39:29.935007+00:00'
    date_released: '2021-09-10'
    submitter_comment: ''