type: position_score
table:
  filename: ENCFF243GGQ.tabix.bed.gz
  header_mode: none
  zero_based: true
  format: tabix
  chrom:
    column_index: 0
  pos_begin:
    column_index: 1
  pos_end:
    column_index: 2
scores:
- id: ATAC-seq_ENCSR694OWY
  column_index: 3
  type: float
  desc: signal
  histogram:
    type: number
    number_of_bins: 100
meta:
  summary: 'ATAC-seq ENCSR694OWY [TISSUE: Homo sapiens spleen tissue male adult (26
    years)]'
  description: '**status**: released


    **biological\_replicates**: Rep 1


    **summary**: male adult (26 years)


    **output\_type**: pseudoreplicated peaks


    **audit\_internal\_action**: Released analysis {ENCAN913DES|/analyses/ENCAN913DES/}
    has in progress subobject quality standard {encode4-atac-seq|/quality-standards/encode4-atac-seq/}


    **audit\_not\_compliant**: According to ENCODE4 standards, overlap peaks files
    in ATAC-seq assays processed by the uniform processing pipeline should have FRiP
    (fraction of reads in called peak regions) scores > 0.3. FRiP scores 0.2-0.3 are
    acceptable, and < 0.2 are not compliant. {ENCFF243GGQ|/files/ENCFF243GGQ/} processed
    by ATAC-seq ENCODE4 v1.9.1 GRCh38 pipeline  has a FRiP score of 0.13.


    **audit\_warning**: Transcription Start Site (TSS) enrichment values for alignments
    to the human genome GRCh38 are concerning when < 5, acceptable between 5 and 7,
    and ideal when > 7. ENCODE processed file {ENCFF933VBN|/files/ENCFF933VBN/} processed
    by ATAC-seq ENCODE4 v1.9.1 GRCh38 pipeline has a TSS enrichment value of 6.381710600380918.'
  labels:
    reference_genome: hg38/genomes/GRCh38-hg38
    accession: ENCSR694OWY
    status: released
    assay_term_name: ATAC-seq
    simple_biosample_summary: male adult (26 years)
    biosample_summary: Homo sapiens spleen tissue male adult (26 years)
    replication_type: unreplicated
    biosample_ontology: /biosample-types/tissue_UBERON_0002106/
    perturbed: false
    doi: 10.17989/ENCSR694OWY
    date_created: '2019-05-29T06:17:06.867157+00:00'
    date_released: '2022-06-16'
    submitter_comment: Despite lower enrichment scores and peaks, sequence-based predictive
      models (neural networks) fit to these data reveal useful motifs and motif annotations.
      Given the value of these rare samples, we release them with an enrichment QC
      warning indicating that these data likely have lower sensitivity for detecting
      accessible regulatory elements.